IB Biology HL D2.1.10 Down syndrome
IB Biology HL D2.1.10 Down syndrome

IB Biology syllabusFirst assessment 2025
Practise linking non-disjunction in meiosis to trisomy 21, karyograms and age-related data for Down syndrome questions.
How this is tested
- explain how failed chromosome separation can produce a gamete with an extra chromosome
- link fertilisation involving an abnormal gamete to a zygote with trisomy 21
- interpret karyograms or graphs to connect chromosome number, age and syndrome risk
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