D2.2.3 (HL)—Control of mRNA degradation Topic Practice
D2.2.3 (HL)—Control of mRNA degradation Topic Practice

IB Biology syllabusBiology SL/HLFirst assessment 2025
Students practise explaining how mRNA lifespan is regulated via structural features like the poly-A tail and nuclease action.
How this is tested
- interpret how progressive poly-A tail shortening limits translation duration and triggers mRNA decay
- explain how endonucleases or exonucleases act on mRNA structure to terminate gene expression
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