C1.1.4—Enzymes as globular proteins
Enzymes are usually globular proteins whose folded active-site pockets bind substrates and catalyse specific reactions in living cells during catalysis.
- Syllabus
- First assessment 2025
- Objective
- C1.1.4
- Level
- HL
Exam analysis
Chance of appearing3%of analysed past papers
Latest appearanceMay 2023
Most common paperPaper2
Typical marks1–6
Common command terms
- Define
- State
Recent exam appearances
May 2023Paper1 ["HL"] · TZ127[ 1 ]C1.1.4—Enzymes as globular proteins
November 2013Paper2 ["HL"] · TZ07(b)[ 6 ]C1.1.4—Enzymes as globular proteins
May 2013Paper2 ["HL"] · TZ24(a)[ 1 ]C1.1.4—Enzymes as globular proteins
Practice this objective
Coverage 2013–2023 · Updated 15 Jul 2026
Concept essentials
- Most enzymes are globular proteins with specific folded shapes.
- The active site is the enzyme region where substrate binds.
- Amino acid sequence contributes to enzyme structure.
- Substrate specificity follows from active-site shape and chemistry.