D3.2.1—Haploid gametes + fusion = diploid zygote

Haploid gametes fuse at fertilization to restore diploid chromosome number in the zygote and combine alleles from two parents in inheritance problems.

Syllabus
First assessment 2025
Objective
D3.2.1
Level
HL

Exam analysis

Chance of appearing1%of analysed past papers
Latest appearanceMay 2018
Most common paperPaper1
Typical marks1

Common command terms

  • Identify

Recent exam appearances

May 2018Paper1 ["HL"] · TZ110[ 1 ]D3.2.1—Haploid gametes + fusion = diploid zygote
Practice this objective

Coverage 2018–2018 · Updated 16 Jul 2026

Gamete Fusion Restores Diploidy

In the sexual life cycle common to eukaryotes, meiosis makes haploid gametes and fertilization fuses two gametes to form a diploid zygote.

Meiosis halves chromosome number from 2n to n. Fusion combines one maternal and one paternal set, restoring 2n without chromosome number doubling in every generation.

A diploid individual normally carries two copies of each autosomal gene, one on each homologous chromosome. Each gamete carries one copy, and the zygote receives two again.

A human sperm and ovum each contain 23 chromosomes; after nuclear fusion the zygote contains 46.

Fertilization combines two haploid sets; it does not copy one gamete or make the zygote genetically identical to either parent.

Haploid gametes + fusion = diploid

Assessment in practice

1 marks
How it is assessed

This objective is assessed through multiple choice, commonly using Identify.

Command terms

Identify

What earns marks

Build the answer around this relationship: Gametes are haploid so fusion can restore the diploid number.

Representative question

Question 1

[Maximum number: 1]

For what reason do gametes contain only one allele of each gene?

A

To prevent inbreeding in a population

B

Haploid cells contain only one set of chromosomes

C

The two alleles of a gene are separated during mitosis

D

Crossing over will always produce one allele of a gene

Retrieve the Core Inheritance Route

Core D3.2 is secure when the student can move from allele rules into predictions and evidence: gametes form genotypes, genotypes can produce phenotypes, different dominance patterns need different notation, and pedigrees or plots require evidence-based interpretation.

  • haploid gametes carry one allele and fertilization restores a diploid genotype
  • dominance, codominance, incomplete dominance, environment, and plasticity affect the observed trait
  • PKU, ABO, sex determination, and haemophilia use different inheritance rules and notation
  • pedigrees infer inheritance patterns and box plots summarize continuous variation

Solve Core Inheritance Questions

Core inheritance exam questions reward disciplined reasoning. First identify the inheritance rule, then write the correct notation or evidence, then state the phenotype, ratio, or conclusion. This prevents the common mistake of writing definitions without solving the genetic problem.

  • Use allele and genotype notation correctly for monohybrid, ABO, PKU, haemophilia, and sex-determination contexts.
  • Connect genotype, dominance pattern, environment, or plasticity to phenotype.
  • Use pedigree or box-plot evidence to justify an inheritance or variation conclusion.

Concept essentials

  • Gametes are haploid so fusion can restore the diploid number.
  • A zygote receives chromosomes and alleles from both parents.
  • Fertilization connects chromosome number with inheritance across generations.