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D1.2.5—Translation

Translation decodes mRNA at ribosomes so codons specify the amino acid order of a growing polypeptide chain during protein synthesis.

Syllabus
First assessment 2025
Objective
D1.2.5
Level
HL

Exam analysis

Chance of appearing3%of analysed past papers
Latest appearanceNovember 2024
Most common paperPaper2
Typical marks4–8

Common command terms

  • Outline
  • Explain
  • Describe

Scoring notes

Common mistake
Naming RNA polymerase as the enzyme for translation instead of locating translation at ribosomes.

Recent exam appearances

November 2024Paper2 ["HL"] · TZ07(a)[ 4 ]D1.2.5—Translation
November 2020Paper2 ["HL"] · TZ06(c)[ 8 ]D1.2.5—Translation
November 2014Paper2 ["HL"] · TZ05(b)[ 8 ]D1.2.5—Translation
Practice this objective

Coverage 2014–2024 · Updated 16 Jul 2026

Concept essentials

  • Translation occurs on ribosomes in the cytoplasm or on rough endoplasmic reticulum.
  • mRNA codons determine the amino acid sequence of the polypeptide.
  • tRNA anticodons pair with codons while tRNA carries specific amino acids.
  • Peptide bonds join amino acids as the ribosome moves along mRNA.
ConceptIB Biology HL