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D1.2.14 (HL)—Non-coding sequences in DNA

Non-coding DNA includes sequences that regulate genes, protect chromosome ends or code for functional RNA rather than polypeptides in genomes.

Syllabus
First assessment 2025
Objective
D1.2.14
Level
HL

Exam analysis

Chance of appearing10%of analysed past papers
Latest appearanceNovember 2024
Most common paperPaper1
Typical marks1

Common command terms

  • State

Scoring notes

Common mistake
Equating non-coding DNA with having no function.

Recent exam appearances

November 2024Paper1 ["HL"] · TZ027[ 1 ]D1.2.14 (HL)—Non-coding sequences in DNA
November 2022Paper2 ["HL"] · TZ04(c)(ii)[ 1 ]D1.2.14 (HL)—Non-coding sequences in DNA
May 2021Paper1 ["HL"] · TZ126[ 1 ]D1.2.14 (HL)—Non-coding sequences in DNA
May 2019Paper2 ["HL"] · TZ22(a)(iii)[ 2 ]D1.2.14 (HL)—Non-coding sequences in DNA
May 2019Paper1 ["HL"] · TZ214[ 1 ]D1.2.14 (HL)—Non-coding sequences in DNA
Practice this objective

Coverage 2013–2024 · Updated 16 Jul 2026

Concept essentials

  • Non-coding DNA can regulate transcription.
  • Telomeres protect the ends of chromosomes.
  • Some DNA sequences code for functional RNAs such as tRNA or rRNA.
  • Introns are removed from eukaryotic RNA before mature mRNA is translated.
ConceptIB Biology HL