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C2.1.12 (HL)—Intracellular receptors

Intracellular receptors bind small hydrophobic signals inside the cytoplasm or nucleus and often regulate transcription directly, linking signal detection to a specific target-cell response.

Syllabus
First assessment 2025
Objective
C2.1.12
Level
HL

Concept essentials

  • Intracellular receptors bind ligands that can cross the plasma membrane.
  • Steroid hormones commonly act through cytoplasmic or nuclear receptors.
  • Hormone-receptor complexes can regulate transcription of specific genes.
  • Intracellular receptor effects often depend on changes in protein synthesis.
ConceptIB Biology HL