D3.1.16 (HL)—Blastocyst and implantation
A blastocyst is an early embryo that has developed into a hollow ball of cells before implantation in the uterine lining.
- Syllabus
- First assessment 2025
- Objective
- D3.1.16
- Level
- HL
A blastocyst is an early embryo that has developed into a hollow ball of cells before implantation in the uterine lining.

Coverage 2012–2012 · Updated 16 Jul 2026
After early cleavage, the embryo forms a blastocyst whose outer cells attach to and invade the uterine lining during implantation.
The inner cell mass forms the embryo; the outer trophoblast helps attachment and later placenta formation. Implantation connects embryonic development to maternal support.
Distinguish cleavage; blastocyst formation; implantation; and later organ development in sequence.
A blastocyst reaches the uterus and its trophoblast attaches to the endometrium, allowing implantation to begin.
Fertilization in the oviduct is not implantation; implantation requires later attachment to the uterine lining.
This objective is assessed through multiple choice, commonly using Identify.
Identify
Build the answer around this relationship: A blastocyst is an embryo, not an unfertilized egg.
Representative question
What is a blastocyst?
An unfertilized egg surrounded by follicle cells
An unfertilized egg cell expelled by menstruation
The follicle when it has swelled up with fluid
The embryo when it has become a hollow ball of cells
D
HL D3.1 is about ordered mechanisms and evidence judgment: endocrine control, gametogenesis contrast, one-sperm fertilization, early embryo stages, hCG detection, placental exchange, birth feedback, and HRT evaluation.
HL D3.1 moves from reproductive events into control and evidence. The strongest answers keep sequences in order: endocrine axis at puberty, gametogenesis outcomes, fertilization blocks, blastocyst implantation, hCG testing, placental exchange, childbirth feedback, and HRT evaluation.