C2.2.1—Neurons
Neurons are specialized cells with dendrites, cell bodies, axons and terminals arranged to receive, conduct and pass on nerve impulses.
- Syllabus
- First assessment 2025
- Objective
- C2.2.1
- Level
- HL
Neurons are specialized cells with dendrites, cell bodies, axons and terminals arranged to receive, conduct and pass on nerve impulses.

Coverage 2012–2024 · Updated 15 Jul 2026
Neurons are specialized cells that receive, integrate and transmit information using membrane potentials and neurotransmitters.
Dendrites receive inputs, the cell body integrates them, and an axon carries action potentials to terminals. Ion channels and synapses connect electrical changes inside one neuron with chemical communication between neurons. This division of labour lets the cell preserve a signal while passing it to the next stage.
Identify the functional regions:
A sensory neuron converts pressure at the skin into receptor-potential changes and action potentials that reach the central nervous system.
Neuron shape varies with function; not every neuron has the same dendrite or axon arrangement.
This objective is assessed through experimental design, commonly using Label / Draw / State.
Label / Draw / State / Distinguish / Identify
Build the answer around this relationship: Dendrites receive signals and conduct them toward the cell body.
Representative question
Draw a labelled diagram of a motor neuron.
Official answer image from the markscheme.
Award [1] for each of the following clearly drawn and correctly labelled:
Cell body; shown with a nucleus.
Nucleus correctly labelled.
Axon; shown as double line longer than the longest dendrite.
Myelin sheath/Schwann cells; surrounding the axon.
Nodes of Ranvier; shown in axon.
Dendrites; shown extending from the cell body.
Motor end plates; not covered by myelin sheath and ending with buttons/dots.
Award any of the above marking points to a clearly drawn annotated diagram.
Preserve all accept/do not accept/award/both-needed/max guidance from the official markscheme.
Neurons carry electrical impulses in the nervous system; motor, sensory, and relay neurons differ in axon, dendrite, and cell body arrangement. Sodium-potassium pumps use ATP to move 3 Na+ out and 2 K+ in; ion gradients make the resting axon polarized at about -70 mV. A nerve impulse is a propagated action potential along a nerve fibre; stimulus-triggered sodium influx reverses membrane polarity. Larger axon diameter lowers resistance and increases impulse speed; myelin sheaths and nodes of Ranvier enable faster saltatory conduction. Synapses connect neurons to neurons, muscles, or glands; chemical synapses transmit one way across a narrow synaptic cleft. Action potentials open voltage-gated Ca2+ channels in presynaptic terminals; Ca2+ causes vesicle fusion and neurotransmitter exocytosis into the cleft. Neurotransmitters diffuse and bind receptors on the postsynaptic membrane; EPSPs depolarize the membrane and make threshold more likely.