CAIE IGCSE Biology 17.1 Chromosomes Genes and Proteins Questions

Practise allele definitions, protein synthesis, selective gene expression and chromosome-number questions using mRNA, specialised cells, chromosome pairs and ploidy evidence.

Syllabus
2026–2028
Course
Biology 0610

Exam points

  • define an allele as an alternative form of a gene and distinguish it from chromosomes or proteins
  • explain how amino-acid sequence determines protein shape and function, including sickle haemoglobin changes
  • trace protein synthesis from a gene in the nucleus through mRNA to ribosome-based amino-acid assembly
  • explain cell specialisation by linking selective gene expression to the proteins a cell needs
  • distinguish haploid gametes from diploid body cells or zygotes using one versus two chromosome sets
  • interpret chromosome diagrams or species data to calculate haploid or diploid chromosome numbers
  • state that human diploid cells have 23 chromosome pairs, or 46 chromosomes in total

Question 1

[Maximum number: 2]

A scientist investigated sexual reproduction in flowering plants.

Fig. 2.1 shows the procedure for crossing two plants of the same species.

Fig. 2.1 shows the procedure for crossing two plants of the same species.

The scientist collected the seeds and germinated them. The leaves and flowers of the offspring plants showed phenotypic variation as they were not all identical to the parent plants.

The scientist then investigated the chromosomes of all the offspring plants and found that they had exactly the same number of chromosomes as the parent plants.

Define the term chromosome.

Question 2

[Maximum number: 4]

Question (a)

(a)

A gene is involved in the production of the enzyme alcohol dehydrogenase.

[ 4 ]

Question (i)

(i)

Define the term gene.

[ 2 ]

Question (ii)

(ii)

Describe the role of ribosomes in the synthesis of proteins such as enzymes.

[ 2 ]

Question 3

[Maximum number: 9]

Question (a)

(a)

Fig. 5.1 shows the stages involved in protein synthesis.

Fig. 5.1

Fig. 5.1

[ 6 ]

Question (i)

(i)

State the names of the parts labelled X, Y and Z in Fig. 5.1.

X

Y
Z

[ 3 ]

Question (ii)

(ii)

State what determines the sequence of the amino acids in the protein that is produced.

[ 1 ]

Question (iii)

(iii)

Explain why the sequence of amino acids is important in the production of receptor molecules for neurotransmitters.

[ 2 ]

Question (b)

(b)

Explain why body cells can have different specialised functions even though they contain the same genes.

[ 2 ]

Question (c)

(c)

Allele frequency in a population can be changed by natural selection and artificial selection.

State the meaning of the term allele.

[ 1 ]
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