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CAIE IGCSE Biology 17.1.6 Amino Acid Sequence & Protein Shape

Practise explaining how different amino-acid sequences produce proteins with different three-dimensional shapes.

Syllabus
2026–2028
Course
Biology 0610

Exam points

  • state that different amino-acid sequences cause protein molecules to fold into different shapes
  • link a changed protein shape to altered function, binding or cell structure
  • apply the relationship to haemoglobin changes that produce rigid, sickle-shaped red cells

17.1.6—Different sequences of amino acids question 1

[Maximum number: 3]

Fig. 2.1 shows a dwarf sunflower and a tall sunflower, Helianthus annuus. The height of the dwarf sunflower is 0.45 m and the height of the tall sunflower is 4.5 m .

not to scale

not to scale

Dwarf plants like the one in Fig. 2.1 have mutant alleles.

Shoot growth in plants is controlled by auxins. An enzyme in shoot tips converts molecules of an amino acid into auxins as shown in Fig. 2.2.

Fig. 2.2

Fig. 2.2

Explain how a mutation in DNA results in an abnormal enzyme which does not catalyse the reaction shown in Fig. 2.2.

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