CAIE IGCSE Biology 14 Coordination & Response
Review nervous and hormonal coordination, sense organs, homeostasis and tropic responses through diagrams and experimental data.
- Syllabus
- 2026–2028
- Course
- Biology 0610
Review nervous and hormonal coordination, sense organs, homeostasis and tropic responses through diagrams and experimental data.
Heart rate is influenced by electrical impulses from the brain.
State the name of the type of cell that conducts electrical impulses to the heart.
(motor / effector) neuron(e) / nerve (cell) ;
R relay / sensory / SAN / pacemaker
The eye is a sense organ that is part of the nervous system.
Explain why the eye can be described as a sense organ.
contains (a group of) receptor cells ; that, detect / respond, to, light / (specific) stimuli ;
State the two parts of the central nervous system.
1
2
brain ; spinal cord ;
A in either order
Fig. 5.1 is a diagram of a section through the human eye.

Fig. 5.1
Draw an X on Fig. 5.1 to identify the blind spot.
blind spot labelled ;
Table 5.1 shows some of the parts labelled in Fig. 5.1, their names and their functions.
Complete Table 5.1.

Table 5.1
Complete correct answer:
Complete Table 5.1:
- retina: letter H; contains receptor cells / rods and cones.
- optic nerve: letter G; transmits impulses to the central nervous system.
- cornea: letter D; refracts light / allows light to enter the eye.
Marking guidance:
Award one mark for each correct row, maximum 3 marks.
State the names of the two effectors that contract and relax during the pupil reflex. and
circular muscle and radial muscle ;
A in either order
Explain why a person is unable to focus on distant objects if the suspensory ligaments become permanently overstretched.
any three from:
ciliary muscles relax ;
suspensory ligaments can no longer become taut ;
lens, is not stretched / remains wide ;
angle of refraction remains unchanged / AW ;
The endocrine system in mammals produces hormones.
Define the term hormone.
(i)
chemical / substance, produced by a gland ; transported in the blood (plasma) ; alters the activity of one of more specific target, organs / tissues / cells ;
The responses of the human body to danger are coordinated by the nervous and endocrine systems.
Fig. 4.1 shows the sequence of events that occurs in response to a dangerous situation that is detected by the eyes.

Fig. 4.1
State the tissue in the eye that converts light energy into nerve impulses.
retina ;
State the part of the eye that has the highest concentration of light-sensitive cells and gives the most detailed image.
fovea ;
State the type of neurone that conducts impulses from the eye to the brain.
sensory (neurone / nerve cell) ;
State the nerve that contains these neurones that conduct impulses from the eye to the brain.
optic ;
Identify the organ labelled P.
spinal cord ;
Identify the gland labelled Q.
adrenal (gland) ;
Complete Table 4.1 to describe the effects of the hormone released when a person is in a dangerous situation.

Table 4.1
| organ | effect of the hormone |
|---|---|
| heart | increased pulse / heart rate / beat |
| liver | conversion of glycogen to glucose / increased blood glucose concentration |
| lungs | increased rate / depth of breathing |
| eyes | dilated pupils / radial muscles in iris contract |
Explain the advantages of coordinating the response to a dangerous situation using both the nervous system and the endocrine system.
nervous system, responds quickly / immediately ; ora idea that (nerve) impulses travel to, (specific) muscles / (adrenal) glands
/ effector(s) ;
effects of endocrine system are long lasting ; ora
hormones / adrenaline, travels throughout the body / allows multiple (target) organs to respond (to same signal) ;
idea that less energy required than to have nerves going to every, cell / tissue ; stimulate both voluntary and involuntary responses (simultaneously) ; more effective / enhanced, response (than using one system alone) ;
Plants also make hormones.
State the name of one hormone made by plants.
auxin ;
Fig. 6.1 shows the changes in glucose concentration of the blood.

Fig. 6.1
Name the process that maintains blood glucose concentration within set limits.
homeostasis/negative feedback ;
Name the hormone that would be secreted in response to the increasing blood glucose concentration at A in Fig. 6.1.
insulin ;
Name an organ that is responsible for the decrease in blood glucose concentration after B in Fig. 6.1.
liver / muscle / pancreas ;
Name the compound that is converted to glucose at C in Fig. 6.1.
glycogen ;
Describe the symptoms and treatment of Type 1 diabetes.
Symptoms:
fatigue / AW ;
thirst / AW ;
increased urination/glucose in urine/fruity breath/ketosis/flushed face; weight loss / nausea / vomiting / abdominal pain / hunger ; blurred vision / glaucoma ; behavioural changes / confusion / faint / unconscious / coma(tose)/ dizzy / rapid breathing/deep breathing ; slow (wound) healing/poor circulation ;
Treatment: insulin ; by injection/insulin pump ; regular blood glucose tests ; regular meals/controlled diet ;
[max 5]
Marking guidance:
max 3 from either section
A weakness I death
A meal plan / healthy eating / monitoring carbohydrates / avoid sugary foods, drinks and fruit juices / eat complex carbohydrates / intake of sugar if blood sugar concentration is too low
[Total: 9]