CAIE IGCSE Biology 10 Diseases & Immunity
Practise identifying pathogens, tracing disease transmission and explaining body defences, immunity and disease control.
- Syllabus
- 2026–2028
- Course
- Biology 0610
Practise identifying pathogens, tracing disease transmission and explaining body defences, immunity and disease control.
Campylobacter is a bacterium that can cause food poisoning.
Which word describes Campylobacter?
antibody
disease
pathogen
symptom
C
Meningitis is a transmissible disease. One form of the disease is caused by the bacterium Neisseria meningitidis.
Define the term transmissible disease.
(disease is caused by) a pathogen ; passes from one host to another ;
The spread of meningitis can be controlled by using vaccines.
Explain how vaccination provides active immunity.
1 (vaccine contains) harmless / attenuated / dead / AW, form of, (named) pathogen / antigen ;
2 (antigens/vaccine) stimulate an immune response ;
3 ref to lymphocytes ;
4 lymphocytes / white blood cells, make antibodies ;
5 ref to specificity ;
6 production of memory cells ;
7 rapid, immune response / AW, if exposed to same, pathogen / antigen ;
8 gives long-term immunity ;
9 AVP ;
If meningitis disappears from a country, explain why the vaccine should continue to be used in that country.
1 bacteria may still be present (in the population) ;
2 in carriers / in people who have no symptoms ;
3 infected people moving into the, country / area / AW ;
4 if few people are, immune / vaccinated, bacterium is more likely to be transmitted ;
5 idea of herd immunity ;
6 some people cannot respond to, antigens / vaccines ;
7 protects people who travel to other countries ;
8 booster vaccinations are sometimes required) / AW ;
MP5 A new people arriving in a
country (who are not vaccinated)
MP6 e.g. people with
HIV / babies / elderly
People who have meningitis are treated with injections of antibodies to give them passive immunity.
Suggest why the antibodies must be injected rather than taking them by mouth.
1 antibodies are made of protein ;
2 proteins / antibodies, are digested / denatured, in the alimentary canal ;
3 direct route to site of infection ;
Explain why passive immunity does not give long-term protection against diseases, such as meningitis.
1 no (active) immune response ;
2 no memory cells ;
3 antibodies are broken down in the body ;
4 antibodies are not made by body's own lymphocytes ;
Fig. 6.1 is a diagram of the virus that causes measles.

Fig. 6.1
Viruses and some bacteria are pathogenic. Diseases caused by pathogens are transmissible.
State two ways that a pathogen can be transmitted indirectly.
food ;
contaminated surfaces ;
animals ;
air ;
water ;
soil ;
The body has barriers to defend itself against pathogens.
State two mechanical barriers of the body.
skin / epidermis ;
hairs in nose ;
mucous membrane ;
mucus ;
ear wax ;
Some white blood cells produce antibodies as part of the body's defence against pathogens.
Describe the role of antibodies in defence of the body.
a pathogen has antigens (on their surface) ;
ref. to specificity / antibodies have complementary shape (to antigen) ;
lock onto (specific) antigens / pathogen ;
destroy pathogens ;
marking for destruction / phagocytosis ;
AVP ;
The immunity gained after infection by a pathogen is active immunity.
Explain how active immunity differs from passive immunity.
long-term / ref. to permanent / protects against some recurring diseases ; produces memory cells ;
antibodies are produced (by the body) ;
slower response ;