D2.1.8—Identification of mitosis phases

Mitosis phases can be identified from chromosome condensation, equator alignment, chromatid separation and nuclear membrane reformation in actively dividing cells.

Syllabus
First assessment 2025
Objective
D2.1.8
Level
HL

Exam analysis

Chance of appearing1%of analysed past papers
Latest appearanceMay 2014
Most common paperPaper1
Typical marks1

Common command terms

  • Identify

Recent exam appearances

May 2014Paper1 ["HL"] · TZ24[ 1 ]D2.1.8—Identification of mitosis phases
Practice this objective

Coverage 2014–2014 · Updated 16 Jul 2026

Chromosome Features Identify Mitosis Stages

Identify a mitosis phase from the position and appearance of chromosomes, using several features rather than cell shape alone.

Phase Reliable visible cues
Prophase Chromosomes condense; the nuclear envelope begins to disappear
Metaphase Condensed chromosomes align at the cell equator
Anaphase Sister chromatids separate and move toward opposite poles
Telophase Chromosomes reach the poles and new nuclear envelopes form

Two groups of V-shaped chromatids moving away from the equator indicate anaphase, whether seen in a diagram, a prepared root-tip cell or a micrograph.

A dark stain or rounded cell outline is not enough to identify a phase. Confirm chromosome condensation, alignment or separation and nuclear-envelope state.

Identification of mitosis phases

Assessment in practice

1 marks
How it is assessed

This objective is assessed through multiple choice, commonly using Identify.

Command terms

Identify

What earns marks

Build the answer around this relationship: Condensed unaligned chromosomes suggest prophase.

Representative question

Question 1

[Maximum number: 1]

The following shows a micrograph.

How many cells are in metaphase?

A

2

B

3

C

5

D

7

Core Cell Division

  • Cell division produces daughter cells for growth, repair or reproduction; cytokinesis divides cytoplasm by a contractile ring in animals or a cell plate in plants.
  • DNA replication creates sister chromatids joined at centromeres before nuclear division.
  • Mitosis preserves chromosome number: chromosomes condense, align, sister chromatids separate and nuclei reform, producing genetically identical nuclei.
  • Meiosis follows one replication with two divisions: homologous chromosomes separate in meiosis I and sister chromatids in meiosis II, producing haploid cells.
  • Crossing over, independent orientation and random fertilization generate allele combinations.
  • Non-disjunction is failed chromosome separation and can produce aneuploid cells, including trisomy 21.
  • Identify stages in micrographs from chromosome condensation, equatorial alignment, separation and nuclear-envelope cues.

Concept essentials

  • Condensed unaligned chromosomes suggest prophase.
  • Chromosomes at the equator indicate metaphase.
  • Separated chromatids moving to poles indicate anaphase.
  • Re-forming nuclei around chromosome groups indicate telophase.