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D1.1.9 (HL)—DNA proofreading

DNA proofreading explains how DNA is copied, checked, amplified or analysed through specific strand relationships, enzyme functions and molecular techniques.

Syllabus
First assessment 2025
Objective
D1.1.9
Level
HL

Exam analysis

Chance of appearing2%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper1A
Typical marks1–4

Common command terms

  • Identify
  • Explain

Scoring notes

Common mistake
Saying helicase forms new strands instead of unwinding DNA and breaking hydrogen bonds.

Recent exam appearances

November 2025Paper2 ["HL"] · TZ19(a)[ 4 ]D1.1.9 (HL)—DNA proofreading
May 2025Paper1A ["HL"] · TZ19[ 1 ]D1.1.9 (HL)—DNA proofreading
Practice this objective

Coverage 2025–2025 · Updated 16 Jul 2026

Concept essentials

  • DNA proofreading depends on matching each strand, enzyme or laboratory step to its exact function.
  • Template strands and complementary base pairing give dna proofreading its copying accuracy.
  • DNA proofreading is clearer when amplification, separation and profiling are not confused.
  • Molecular evidence for dna proofreading must be interpreted from bands, isotopes, primers or enzyme roles.
ConceptIB Biology HL