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C3.2.3—Blood clotting

Blood clotting explains how a specific barrier, pathogen interaction, immune mechanism or treatment response contributes to protection against infectious disease.

Syllabus
First assessment 2025
Objective
C3.2.3
Level
HL

Exam analysis

Chance of appearing12%of analysed past papers
Latest appearanceMay 2023
Most common paperPaper1
Typical marks1

Common command terms

  • Identify
  • Describe
  • State
  • Explain
  • Outline

Scoring notes

Common mistake
Reversing fibrinogen and fibrin in the clotting sequence.

Recent exam appearances

May 2023Paper1 ["HL"] · TZ121[ 1 ]C3.2.3—Blood clotting
May 2022Paper1 ["HL"] · TZ225[ 1 ]C3.2.3—Blood clotting
May 2022Paper1 ["HL"] · TZ122[ 1 ]C3.2.3—Blood clotting
November 2021Paper1 ["HL"] · TZ020[ 1 ]C3.2.3—Blood clotting
May 2019Paper2 ["HL"] · TZ23(b)[ 3 ]C3.2.3—Blood clotting
Practice this objective

Coverage 2012–2023 · Updated 16 Jul 2026

Concept essentials

  • Blood clotting has to be linked to the exact pathogen, cell, molecule or population process involved.
  • The biological effect of blood clotting depends on the sequence from trigger to protective outcome.
  • Clear distinctions within blood clotting prevent confusion with neighbouring immune responses.
  • Evidence for blood clotting is strongest when mechanism and consequence are explained together.
ConceptIB Biology HL