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IB Biology HL 3.2.3 Blood clotting Question Bank

Practise IB Biology HL 3.2.3 by analysing the enzyme cascade and experimental evidence in blood clotting.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • Analyse the sequence from platelet activation to fibrin formation in a clotting cascade.
  • Evaluate the roles of thrombin, platelets and anticoagulants in clot formation.

C3.2.3—Blood clotting question 1

[Maximum number: 1]

Plasma proteins, sCD 62 P and sCD 40 L , are involved in the activation of blood platelets. The von Willebrand factor causes the platelets to stick to blood vessel walls. Fibrinogen is a marker for inflammation of the blood system. All four are biological markers that indicate a risk of thrombosis.

During the 2008 Olympic games held in Beijing, the Chinese authorities temporarily reduced air pollution levels by restricting emissions from motor vehicles and industry. Doctors used this event to test the effects of air pollution on these biological markers. The graph shows the mean percentage changes in the levels of biological markers in volunteers during the study.

Figure for Question C3.2.3—Blood clotting question 1 — IB Biology HL
Figure for Question C3.2.3—Blood clotting question 1 — IB Biology HL

Thromboses, including coronary thrombosis, could be a consequence of a build-up of these biomarkers.

State the role of platelets in thromboses.

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