CAIE IGCSE Biology 11.1 Human Gas Exchange & Ventilation
Practise human gas-exchange questions on airway labels, alveolar diffusion, inspired-expired air, exercise breathing and ventilation mechanics.
- Syllabus
- 2026–2028
- Course
- Biology 0610
Practise human gas-exchange questions on airway labels, alveolar diffusion, inspired-expired air, exercise breathing and ventilation mechanics.
Fig. 6.1 shows part of the human gas exchange system.

Fig. 6.1
Table 6.1 shows the names of some parts of the human gas exchange system, their functions and the letters in Fig. 6.1 that identify the parts.
Complete Table 6.1.

Table 6.1
Complete correct answer:
Complete Table 6.1:
- traps particles before they enter the airway / mechanical barrier to pathogens: hairs in the nose; letter A.
- prevents collapse of the airway: cartilage; letter J / B.
- contracts to decrease the pressure in the thorax: external intercostal muscles; letter F.
- contracts to reduce the pressure / increase the volume in the thorax: diaphragm; letter C.
- protects the lungs from mechanical damage: rib(cage); letter E.
- contain cilia to move mucus out of the airway: trachea / bronchi / bronchiole; letter J / B / G.
- site of gas exchange: alveoli; letter H.
Marking guidance:
Award one mark for each correct row, maximum 7 marks.
Describe and explain how the alveoli are adapted for gas exchange.
any three from:
thin / one cell thick ;
large surface area ;
(which) reduces diffusion distance / AW ;
good blood supply ;
AVP ;
e.g. moist lining / presence of surfactant
Explain the differences in composition between inspired and expired air.
any three from:
less oxygen and more carbon dioxide in expired air (than inspired air) ;
(as) oxygen is required for aerobic respiration ; carbon dioxide is released by respiration ; water vapour increases (as it is released by respiration) ; AVP ;
Physical activity changes the concentration of carbon dioxide in the body.
State where this change is detected and how the body responds to the change.
detected:
either
(carbon dioxide is) in the blood
or
by the brain ;
response:
either
increases, rate / depth, of breathing
or
increases heart rate / AW ;
State the name of a solution that can be used to test for the presence of carbon dioxide gas.
limewater / hydrogencarbonate indicator (solution) / AVP ;
Substances move between blood and tissues at various sites in the circulatory system of mammals.
Oxygen is absorbed into the blood as it passes through the lungs.
State the structures in the lungs where oxygen passes into the blood from the air.
alveoli / alveolus ;