IB Biology HL C1.2 Cell Respiration Questions

Practise IB Biology HL C1.2 with pathway diagrams and data questions covering glycolysis, link reaction, Krebs cycle, chemiosmosis, anaerobic respiration and ATP yield.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • Explain ATP energy transfer through hydrolysis and regeneration, linking ATP production to cellular work.
  • Define cellular respiration and relate oxygen, carbon dioxide and ATP across its stages.
  • Compare human aerobic and anaerobic respiration using lactate, oxygen debt and exercise data.
  • Interpret variables and design rate experiments affecting respiration.
  • Explain NAD/NADH and glycolysis ATP investment, payoff and reduced NAD.
  • Compare lactate formation in humans with yeast fermentation, explaining NAD regeneration and limited ATP.
  • Explain the link reaction, acetyl-CoA formation and mitochondrial location.
  • Trace Krebs-cycle location, reactions, carriers and carbon dioxide release.
  • Trace the ETC, proton pumping, chemiosmosis and ATP synthase in oxidative phosphorylation.
  • Explain oxygen as the terminal electron acceptor and account for water formation.
  • Compare lipids and carbohydrates as respiratory substrates.

Question 1

[Maximum number: 3]

All cells require a supply of energy and can transform the energy that they obtain in different ways.

Explain the properties of ATP that make it useful for distributing energy within cells.

Question 2

[Maximum number: 5]

Monosaccharides can be used to make polysaccharides, and can also be combined with other types of carbon compound to form molecules such as nucleotides.

Outline, with examples, the wide range of uses of adenosine triphosphate (ATP) in cells.

Question 3

[Maximum number: 1]

Which reaction does not cause a net release of energy?

A

ADP combines with inorganic phosphate to form ATP

B

ATP releases inorganic phosphate to form ADP

C

Loss of hydrogen from reduced NAD

D

Oxidation of reduced FAD

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