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IB Biology HL C3.2.8 B Lymphocyte Activation Questions

Explore how antigen presentation and helper-T signals activate B-cells, drive clonal expansion and produce pathogen-specific antibody-secreting plasma cells in IB Biology HL…

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • Explain that an antigen binds to a specific B-cell and that an activated helper T-cell provides the signal that activates the B-cell.
  • Explain that an activated B-cell enters clonal expansion and differentiates into plasma cells that secrete antibodies specific to the presented antigen.

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Study C3.2.8—B-lymphocyte activation conceptsOpen the corresponding Concept lesson for explanations, examples and exam connections.

IB Biology HL C3.2.8 B Lymphocyte Activation Questions question 1

[Maximum number: 3]

Ebola virus disease (EVD) is the disease in humans and other primates that is caused by the Ebola virus. Fruit bats are the reservoir for the virus and are able to spread the disease without being affected. Humans can become infected by contact with fruit bats or with people infected by the virus, their body fluids or equipment used to treat them.

The stacked bar graph shows the epidemiological data for the EVD cases in Conakry, the capital city of Guinea, surrounding suburbs and rural areas in Guinea from the beginning of January 2014 to the end of March 2015.

Figure for Question IB Biology HL C3.2.8 B Lymphocyte Activation Questions question 1 — IB Biology HL

Explain how vaccination can lead to the production of B cells specific to the Ebola virus.

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