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CAIE IGCSE Biology 16.5 Sex Hormones in Humans Questions

Practise human sex-hormone questions by reading menstrual-cycle graphs, locating hormone production sites and explaining FSH, LH, oestrogen and progesterone control.

Syllabus
2026–2028
Course
Biology 0610

Exam points

  • link testosterone and oestrogen to named male and female secondary sexual characteristics during puberty
  • interpret menstrual-cycle diagrams to locate menstruation, ovulation near day 14 and uterine-lining changes
  • identify ovaries and placenta as production sites for oestrogen and progesterone in the cycle and pregnancy
  • explain how FSH, LH, oestrogen and progesterone control follicles, ovulation, the uterine lining and pregnancy

Covered syllabus points

16.5.1—Roles of testosterone and oestrogen16.5.2—Menstrual cycle in terms of changes16.5.3—Sites of production of oestrogen16.5.4—Role of hormones in controlling

Question 1

[Maximum number: 1]

State the name of the hormone that causes voices to deepen at puberty.

Question 2

[Maximum number: 6]

Question (a)

(a)

Fig. 1.1 shows the changes in the concentration of two hormones involved in the menstrual cycle.

Fig. 1.1

Fig. 1.1

[ 6 ]

Question (i)

(i)

State the names of the hormones Y and Z in Fig. 1.1.

Y

Z

[ 2 ]

Question (ii)

(ii)

On Fig. 1.1, sketch a line to show the levels of progesterone through the 28-day menstrual cycle.

[ 2 ]

Question (iii)

(iii)

State the day in the 28-day menstrual cycle when the egg is most likely to be released from a follicle.

[ 1 ]

Question (iv)

(iv)

State the main site of progesterone production during pregnancy.

[ 1 ]

Question 3

[Maximum number: 3]

Chlamydia can damage the reproductive system.

Describe the role of oestrogen at puberty.

Question 4

[Maximum number: 1]

Fig. 1.1 shows the changes in the concentration of two hormones involved in the menstrual cycle.

Fig. 1.1

Fig. 1.1

State the day in the 28-day menstrual cycle when the egg is most likely to be released from a follicle.

Question 5

[Maximum number: 1]

Fig. 1.1 shows the changes in the concentration of two hormones involved in the menstrual cycle.

Fig. 1.1

Fig. 1.1

State the main site of progesterone production during pregnancy.

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