CAIE IGCSE Biology 10.1.12 Vaccination in Disease Control
Practise explaining how vaccination reduces susceptible hosts, transmission and outbreaks across a population.
- Syllabus
- 2026–2028
- Course
- Biology 0610
Practise explaining how vaccination reduces susceptible hosts, transmission and outbreaks across a population.
Cholera is a transmissible disease.
A study was designed to test the effectiveness of a cholera vaccine in an area where outbreaks of cholera occur frequently.
The doctors gave some people in this area the new vaccine.
There was an outbreak of cholera in the area two months after the new vaccine was given.
The people who had symptoms of cholera were monitored in hospital for two days.
Some of the infected people had received the new vaccine and others had not received the vaccine.
The results are shown in Fig. 4.1.

Fig. 4.1
Using the information in Fig. 4.1, discuss how effective the vaccine was at preventing the symptoms of cholera.
any two from:
more, pathogens / diarrhoea / fever, in non-vaccinated group ; ora
some vaccinated people did get symptoms so vaccine not 100 %
effective ; ora
comparative data quote between vaccinated and not vaccinated ;
AVP ;