CAIE IGCSE Biology 10.1 Diseases and Immunity Questions

Practise disease and immunity questions on pathogen transmission, body defences, disease control, vaccination, passive immunity and cholera toxin effects.

Syllabus
2026–2028
Course
Biology 0610

Exam points

  • classify pathogens and distinguish direct, indirect or hygiene-linked transmission scenarios
  • explain body defences using barriers, phagocytes, lymphocytes and antibody production
  • trace vaccination, passive immunity or cholera-toxin sequences using antibodies and osmosis

Question 1

[Maximum number: 1]

Campylobacter is a bacterium that can cause food poisoning.
Which word describes Campylobacter?

A

antibody

B

disease

C

pathogen

D

symptom

Question 2

[Maximum number: 12]

Meningitis is a transmissible disease. One form of the disease is caused by the bacterium Neisseria meningitidis.

Question (a)

(a)

Define the term transmissible disease.

[ 2 ]

Question (b)

(b)

The spread of meningitis can be controlled by using vaccines.

[ 6 ]

Question (i)

(i)

Explain how vaccination provides active immunity.

[ 4 ]

Question (ii)

(ii)

If meningitis disappears from a country, explain why the vaccine should continue to be used in that country.

[ 2 ]

Question (c)

(c)

People who have meningitis are treated with injections of antibodies to give them passive immunity.

[ 4 ]

Question (i)

(i)

Suggest why the antibodies must be injected rather than taking them by mouth.

[ 2 ]

Question (ii)

(ii)

Explain why passive immunity does not give long-term protection against diseases, such as meningitis.

[ 2 ]

Question 3

[Maximum number: 11]

Fig. 6.1 is a diagram of the virus that causes measles.

Fig. 6.1

Fig. 6.1

Question (a)

(a)

Viruses and some bacteria are pathogenic. Diseases caused by pathogens are transmissible.

[ 4 ]

Question (i)

(i)

State two ways that a pathogen can be transmitted indirectly.

[ 2 ]

Question (ii)

(ii)

The body has barriers to defend itself against pathogens.

State two mechanical barriers of the body.

[ 2 ]

Question (b)

(b)

Some white blood cells produce antibodies as part of the body's defence against pathogens.

Describe the role of antibodies in defence of the body.

[ 4 ]

Question (c)

(c)

The immunity gained after infection by a pathogen is active immunity.

Explain how active immunity differs from passive immunity.

[ 3 ]
All question bank results loaded