C3.2.15—Zoonoses

Zoonoses explains how a specific barrier, pathogen interaction, immune mechanism, treatment response or population process contributes to protection against infectious disease.

Syllabus
First assessment 2025
Objective
C3.2.15
Level
SL

Exam analysis

Chance of appearing2%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper1A
Typical marks1

Common command terms

  • State
  • Identify
  • Explain

Scoring notes

Common mistake
Defining zoonoses as diseases from zoos rather than transfer from other animal species.

Recent exam appearances

November 2025Paper1A ["SL"] · TZ118[ 1 ]C3.2.15—Zoonoses
May 2025Paper1A ["SL"] · TZ319[ 1 ]C3.2.15—Zoonoses
May 2025Paper1A ["SL"] · TZ218[ 1 ]C3.2.15—Zoonoses
Practice this objective

Coverage 2025–2025 · Updated 16 Jul 2026

Zoonoses cross from animal reservoirs into people

A zoonosis is an infectious disease that can transfer from another animal species to humans, through several different transmission routes.

Zoonosis Animal link and route to humans
Tuberculosis Some strains can pass from infected cattle or other animals through close exposure or contaminated animal products
Rabies Virus in saliva is commonly transferred by the bite of an infected mammal
Japanese encephalitis Mosquito vectors transfer virus maintained among animal hosts such as pigs and birds
COVID-19 A recently emerged infection that transferred from another species, followed by extensive human-to-human respiratory transmission

Zoonoses are prevalent among human infectious diseases because humans interact with livestock, wildlife, food systems and vectors. Ecology and behaviour change the opportunities for cross-species exposure.

Animal origin does not guarantee efficient human-to-human spread. Identify the reservoir or animal link, the transfer route and whether onward human transmission occurs.

Zoonoses exam focus

Assessment in practice

1 marks
How it is assessed

This objective is assessed through structured response, commonly using State / Identify / Explain.

Command terms

State / Identify / Explain

What earns marks

Mark schemes repeatedly reward named details, correct sequence and clear distinctions between similar processes.

Watch for

Defining zoonoses as diseases from zoos rather than transfer from other animal species.

Representative question

Question 1

[Maximum number: 1]

State the term used for an infectious disease that can transfer from other species to humans.

Defence Against Disease

  • Skin, mucus, cilia, lysozyme and clotting form primary barriers against pathogens.
  • Innate immunity is rapid and broad: phagocytes recognize, engulf and digest pathogens. Adaptive immunity is antigen-specific and forms memory.
  • Helper T-cells coordinate responses; activated B-cells undergo clonal selection, producing antibody-secreting plasma cells and memory cells. A second exposure therefore triggers a faster, stronger response.
  • HIV infects CD4 helper T-cells; their loss weakens immune coordination and can lead to AIDS.
  • Antibiotics target bacterial processes, not viruses. Antibiotic exposure selects resistant variants, which can spread by reproduction or plasmid transfer.
  • Vaccination creates active artificial immunity; high population immunity can indirectly protect susceptible people.
  • Evaluate disease and vaccine claims using reliable sources, trends, controlled comparisons, incidence and efficacy—not raw totals alone.

Concept essentials

  • Zoonoses has to be linked to the exact pathogen, cell, molecule or population process involved.
  • The biological effect of zoonoses depends on the sequence from trigger to protective outcome.
  • Clear distinctions within zoonoses prevent confusion with neighbouring immune responses.
  • Evidence for zoonoses is strongest when mechanism and consequence are explained together.