Compare two recurring synaptic drug mechanisms: neonicotinoids persist at insect acetylcholine receptors, while cocaine blocks dopamine reuptake and prolongs signalling.
Cholinergic synapses use acetylcholine as their neurotransmitter. They are widespread in the body, passing on signals to muscle cells. These synapses are affected by neonicotinoid pesticides.
The diagrams, which are not drawn to scale, show the synapse between two neurons and a detail of the synaptic cleft.
On the diagrams, label:
On the diagrams, label with a letter P a location where a neonicotinoid pesticide could bind.