IB Biology HL 2.2.7 Excitatory postsynaptic potentials Question Bank
Practise IB Biology HL 2.2.7 by analysing how transmitter binding and receptor action initiate postsynaptic responses.
- Syllabus
- First assessment 2025
- Course
- Biology HL
- Level
- HL
Practise IB Biology HL 2.2.7 by analysing how transmitter binding and receptor action initiate postsynaptic responses.
Cholinergic synapses use acetylcholine as their neurotransmitter. They are widespread in the body, passing on signals to muscle cells. These synapses are affected by neonicotinoid pesticides.
The diagrams, which are not drawn to scale, show the synapse between two neurons and a detail of the synaptic cleft.

Explain how acetylcholine initiates an action potential in a postsynaptic membrane.
a. acetylcholine binds to the receptor protein
b. (causing a) change in tertiary structure / conformation of protein
c. diffusion/entry of ions/ Na+through the receptor/channel protein allowed
2 max