IB Biology HL B1.2.5 Effect of Ph and Temperature Questions
Practise IB Biology HL B1.2.5 by explaining how heat and other conditions alter protein conformation and function.
- Syllabus
- First assessment 2025
- Course
- Biology HL
- Level
- HL
Exam points
- Identify increased temperature, extreme pH, salts or heavy metals as conditions that can denature proteins.
- Explain how denaturation disrupts weak bonds and changes protein conformation, including an enzyme active site.
- Relate loss of three-dimensional structure to reduced substrate binding and reduced or lost biological activity.
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IB Biology HL B1.2.5 Effect of Ph and Temperature Questions question 1
[Maximum number: 4]
Proteins carry out many important functions in cells and in organisms.
Outline the process of protein denaturation.
change to conformation/shape/tertiary structure/3-D shape;
bonds within the protein/intramolecular bonds broken/changed;
pH and temperature (outside tolerated ranges) can cause denaturation;
vibrations/heat at high temperatures breaks bonds;
high pH/low pH/extreme pH alters ionization/charges (of amino acids and breaks ionic bonds);
protein cannot carry out its function
OR
active site of enzymes cannot bind substrates/catalyze reaction/no enzyme-substate complex;
permanent/irreversible change (usually)
OR
soluble proteins become insoluble/precipitate;
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