Practise IB Biology HL B1.2.5 by interpreting how heat and pH disrupt protein conformation, then using albumin data to identify denaturation.
Proteins carry out many important functions in cells and in organisms.
Outline the process of protein denaturation.
a change to conformation/shape/tertiary structure/3-D shape;
b bonds within the protein/intramolecular bonds broken/changed;
c pH and temperature (outside tolerated ranges) can cause denaturation;
d vibrations/heat at high temperatures breaks bonds;
e high pH/low pH/extreme pH alters ionization/charges (of amino acids and breaks ionic bonds);
f protein cannot carry out its function
OR
active site of enzymes cannot bind substrates/catalyze reaction/no enzyme-substate complex;
g permanent/irreversible change (usually)
OR
soluble proteins become insoluble/precipitate;
Marking guidance:
Allow any mark points if made clearly on an annotated graph or diagram.
4 max