IB Biology HL B2.3 Cell Specialization Questions

Practise IB Biology HL B2.3 with evidence-led questions on stem-cell potency, differentiation, exchange surfaces and the structure–function adaptations of specialized cells.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • Use insulin-mRNA or signalling-gradient evidence to explain embryonic cell differentiation.
  • Explain how stem cells self-renew and use potency to produce specialized tissues.
  • Classify totipotent, pluripotent and multipotent stem cells by developmental potential.
  • Interpret cell-size graphs to explain falling SA:V ratios and their effect on exchange.
  • Relate microvilli, transport proteins and mitochondria to intestinal or renal absorption.
  • Distinguish thin type I gas-exchange cells from type II surfactant-secreting pneumocytes.
  • Explain how surfactant lowers alveolar surface tension and prevents collapse.
  • Compare cardiac and skeletal muscle; link cardiac branching and gap junctions to impulse conduction.
  • Relate the sperm mid-piece’s mitochondria to ATP production for movement.
  • Label mature human egg diagrams with the nucleus, cytoplasm and surrounding structures.

Question 1

[Maximum number: 1]

A liver cell and a neuron developed from the same zygote both retain genes L and N. RNA from L is abundant in the liver cell but scarce in the neuron; RNA from N shows the opposite pattern.

Which interpretation best explains how these cells can become specialized?

A

The two cells must use different genetic codes to translate the same genes.

B

Each cell must delete every gene that it does not currently express.

C

Different expression of shared genes can produce different sets of proteins.

D

Retaining the same genes requires the two cells to have identical protein production.

Question 2

[Maximum number: 3]

Outline reasons for the therapeutic use of stem cells.

Question 3

[Maximum number: 1]

State what change there has been in the cell surface area to volume ratio in red blood cell 1.

Question 4

[Maximum number: 1]

The micrograph shows part of a cell.

Figure for Question 4 — IB Biology HL

Which principal function is this cell likely to have, as judged by its cell structure and organelles?

A

High rate of protein processing

B

High rate of absorption

C

High rate of photosynthesis

D

High rate of movement

Question 5

[Maximum number: 2]

Measurements of the lung capacity of a student were recorded using a spirometer and displayed with a data logger. Initially the student was at rest, then changed to carrying out strenuous exercise. The results are displayed in the graph.

Figure for Question 5 — IB Biology HL

Outline the function of pneumocytes in the lungs.

Question 6

[Maximum number: 1]

Which features are found in both cardiac and striated muscle?

A

Nuclei and branched myofibrils

B

Sarcomeres and unbranched myofibrils

C

Mitochondria and branched myofibrils

D

Sarcomeres and mitochondria

Question 7

[Maximum number: 5]

Draw a labelled diagram of a mature human egg.

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