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IB Biology HL B1.2 Proteins Question Bank

Practise IB Biology HL B1.2 with questions that move from amino-acid and peptide-bond diagrams to protein folding, interactions, denaturation and structure–function reasoning.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • draw and label amino acids and peptide bonds, showing condensation products and water release in dipeptides
  • explain primary-to-quaternary structure using hydrogen, ionic, disulfide and hydrophobic R-group interactions
  • deduce protein shape and function from polarity, alpha helices, beta sheets, globular or fibrous form

B1.2 Proteins question 1

[Maximum number: 7]

Question (a)

(a)

Some of the twenty amino acids that are linked together to make polypeptides in human cells are essential in the diet and others are not. Distinguish between essential and non-essential amino acids.

[ 2 ]

Question (b)

(b)

The molecules of all amino acids include an amine group, a carboxyl group and an R-group. Draw a diagram to show the structure of an amino acid molecule.

[ 3 ]

Question (c)

(c)

The R-groups of amino acids are very diverse chemically. Interaction between R-groups in different parts of a polypeptide helps to determine the tertiary structure of a protein. List two types of interaction between R-groups.

[ 2 ]

B1.2 Proteins question 2

[Maximum number: 2]

Question (a)

(a)

Label a peptide bond in the diagram of a polypeptide.

Figure for Question (a) — IB Biology HL
[ 1 ]

Question (b)

(b)

Outline the primary structure of proteins.

[ 1 ]
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