D3.3.11 (HL)—Blood supply changes
Blood supply changes during exercise redistribute flow so more blood reaches skin for heat removal in human physiology in human physiology.
- Syllabus
- First assessment 2025
- Objective
- D3.3.11
- Level
- HL
Blood supply changes during exercise redistribute flow so more blood reaches skin for heat removal in human physiology in human physiology.

Coverage 2025–2025 · Updated 16 Jul 2026
Arteriolar vasodilation and vasoconstriction redistribute blood so organ supply matches changing metabolic activity while vital functions continue.
| State | Skeletal muscle | Gut | Brain | Kidneys |
|---|---|---|---|---|
| Sleep | Lower flow to most muscle groups than when awake | Depends on digestive activity | Total flow changes little, though regions such as hypothalamus/brainstem can rise during REM | Maintained for excretion and osmoregulation; lying down can raise renal flow |
| Vigorous exercise | Strongly increased | Reduced as blood is redirected | Kept relatively stable | Reduced during prolonged vigorous exercise, but regulation limits disruption |
| Wakeful rest | Lower than during exercise | Increased after a meal for digestion and absorption | Kept relatively stable | Fairly constant overall; posture can alter flow |
Locally active tissues dilate their arterioles, while sympathetic/epinephrine signals can constrict vessels to less immediately required organs and dilate those supplying skeletal muscle.
During vigorous exercise, skeletal-muscle flow rises while gut and renal flow fall; this supplies respiration where demand is greatest.
Redistribution is relative, not complete shut-off. Brain and kidney perfusion must remain sufficient for neural control, excretion and osmoregulation.
This objective is assessed through multiple choice, commonly using Identify.
Identify
Build the answer around this relationship: Exercise increases heat production in muscles.
Representative question
What is a reason for the changes in blood flow during exercise?
Increased blood flow to the kidneys removes waste products from exercise.
Blood flow to the brain decreases so that blood is diverted to the kidneys.
Increased blood flow to the skin removes heat.
Increased blood flow to the digestive system provides more glucose to muscles.
C
HL D3.3 adds kidney and circulation mechanisms. The route is still feedback logic: nephrons filter and reabsorb, the loop of Henle builds a gradient, ADH changes collecting duct permeability, and blood vessels redistribute flow according to activity.
HL homeostasis transfer is about structure-function precision. In kidney answers, say where filtration, reabsorption, salt pumping, water movement, ADH, and aquaporins happen. In blood-flow answers, say which vessels dilate or constrict and how activity changes tissue demand.