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CAIE A-Level Biology 19.1.7 Gene Editing by Insertion, Deletion or Replacement

Practise tracing CRISPR-Cas9 targeting and DNA repair, then apply insertion, deletion or replacement to disease alleles and judge editing outcomes.

Syllabus
2028–2030
Course
Biology 9700
Level
A2

Exam points

  • trace guide-RNA base pairing and Cas9 cleavage at a specific target DNA sequence
  • apply insertion, deletion or replacement to restore function or inactivate a harmful allele
  • judge editing success and specificity from sequence, protein, phenotype or gel evidence

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