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C2.2.2—Resting potential generation

Resting potential is generated when ion pumps and membrane permeability make the inside of an axon negative relative to the outside.

Syllabus
First assessment 2025
Objective
C2.2.2
Level
SL

Exam analysis

Chance of appearing4%of analysed past papers
Latest appearanceNovember 2024
Most common paperPaper2
Typical marks1–2

Common command terms

  • Define
  • Outline
  • Explain
  • State
  • Label

Recent exam appearances

November 2024Paper2 ["SL"] · TZ25(b)[ 2 ]C2.2.2—Resting potential generation
May 2022Paper2 ["SL"] · TZ15(a)[ 1 ]C2.2.2—Resting potential generation
May 2021Paper2 ["SL"] · TZ14(b)[ 2 ]C2.2.2—Resting potential generation
May 2021Paper2 ["SL"] · TZ14(a)[ 1 ]C2.2.2—Resting potential generation
May 2018Paper3 ["SL"] · TZ24(b)(i)[ 2 ]C2.2.2—Resting potential generation
Practice this objective

Coverage 2015–2024 · Updated 15 Jul 2026

Concept essentials

  • The resting axon is negative inside relative to outside.
  • The sodium-potassium pump uses ATP to maintain ion gradients.
  • Three sodium ions are pumped out for every two potassium ions pumped in.
  • Resting potential is an actively maintained state, not an absence of membrane processes.
ConceptIB Biology SL