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IB Biology HL D1.3.2 Base Substitution Consequences Questions

Analyse how a DNA base substitution changes codons and proteins, including silent, missense, nonsense and sickle-cell outcomes in IB Biology HL D1.3.2.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • Deduce the codon and amino-acid consequence of a specified DNA base substitution using the genetic code.
  • Distinguish silent, missense, and nonsense outcomes that can follow from a changed codon.
  • Link a substitution from DNA and primary structure to altered haemoglobin function or sickle-cell phenotype.

IB Biology HL D1.3.2 Base Substitution Consequences Questions question 1

[Maximum number: 5]

Outline the effects of a base substitution mutation in the case of sickle-cell anemia.

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