IB Biology HL D1.3.1 Gene Mutations Questions
Use IB Biology HL D1.3.1 evidence to identify DNA sequence changes and distinguish substitution, insertion and deletion mutation types.
- Syllabus
- First assessment 2025
- Course
- Biology HL
- Level
- HL
Use IB Biology HL D1.3.1 evidence to identify DNA sequence changes and distinguish substitution, insertion and deletion mutation types.
Duchenne muscular dystrophy (DMD) is a sex-linked genetic disorder caused by a recessive allele resulting from mutations in the X-linked dystrophin gene. This causes the degeneration of cardiac and skeletal muscle. These mutations can include deletions, insertions and base substitution mutations.
Distinguish between deletion and insertion mutations.
deletion is loss/removal of bases/nucleotides/part of DNA/gene while insertion is addition of bases/nucleotides/one/more copies of any piece of DNA/gene/chromosome;
Both deletion and insertion needed.
Marking guidance:
Do not award marking point for repeating the definition e.g. "deletion" is bases "deleted" / "insertion" is bases "inserted".