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IB Biology HL 1.3.8 Gene knockout Question Bank

Practise IB Biology HL 1.3.8 by applying gene knockout concepts to exam-style questions.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • identify the relevant biological structure, process or evidence
  • apply the correct biological mechanism to the question
  • evaluate the result using data, adaptation or ecological reasoning

D1.3.8 (HL)—Gene knockout question 1

[Maximum number: 1]

Knockout organisms are used as models in research. The p53 knockout mouse is named after p53, a gene which codes for a protein that normally suppresses the growth of cancerous tumours.

How could scientists use p53 knockout mice in cancer research?

A

To extract tumour suppressor protein from p53 knockout mice for cancer treatments

B

To obtain functional copies of the p53 gene to use in gene replacement therapy

C

To investigate the effect of new anti-cancer drugs on mouse tumours

D

To study the effect of mutations on the expression of the p53 gene

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