IB Biology HL D2.1 Cell and Nuclear Division Questions
Practise IB Biology HL D2.1 by identifying cell-division stages, explaining meiosis outcomes and interpreting chromosome evidence.
- Syllabus
- First assessment 2025
- Course
- Biology HL
- Level
- HL
Practise IB Biology HL D2.1 by identifying cell-division stages, explaining meiosis outcomes and interpreting chromosome evidence.
What describes nuclear division in stem cells?
Clonal selection
Mitosis
Cytokinesis
Meiosis
B
Eukaryotes are a diverse group of organisms, including animals and plants.
Compare and contrast the processes of mitosis and cytokinesis in animal and plant cells.
Similarities: [6 max]
a. (in both plants and animals) produces two genetically identical daughter cells;
b. maintains the chromosome number/genome of cell / produces diploid/2n cells;
c. used for generation of new cells/cell replacement/tissue repair/growth;
d. in prophase the chromatin/chromosome condenses/formation of chromatids/supercoiling of chromosomes;
e. supercoiling of DNA around histones (to form nucleosomes);
f. microtubules/microtubule motors to move chromosomes/chromatids;
g. in metaphase chromosomes align in equator of cell;
h. in anaphase separation of chromatids;
i. in telophase two nuclei/cells form / nuclear membrane/envelope reforms
OR
cytokinesis is the division into two cells;
Differences:
j. in animal cell centrosomes/centrioles facilitates the organization of the mitotic spindle/ spindle poles/microtubules;
k. in plant cells spindle fibres attach to walls;
l. in animal cells, the plasma membrane is pulled inwards around the equator to form a cleavage furrow in cytokinesis
OR
in animal cells actin and myosin pinch cell membrane to split cytoplasm/cytokinesis;
m. in plant cells a cell plate forms (at the equator) to develop into the new cell wall to achieve cytokinesis
OR
in plant cell vesicles (containing pectin) assemble sections of membrane/cell wall (at/across the equator) to achieve splitting/cytokinesis;
Marking guidance:
Max 6 for similarities.
Allow clearly annotated diagrams.
8 max
The genome is the total of all the DNA in an organism, containing all the genetic information required for development and growth.
Distinguish between cell division by mitosis and by meiosis in eukaryote cells.
| Mitosis | Meiosis | |
|---|---|---|
| a. | maintains chromosome number/diploid | halves chromosome number/haploid |
| b. | for growth/repair | for gamete production |
| c. | in somatic cells | in reproductive/sex/gamete cells |
| d. | one division | two divisions |
| e. | no exchange of genetic material between chromosomes/crossing over | exchange of genetic material between chromosomes/crossing over |
| f. | results in two cells | results in 4 cells |
| g. | only divides chromatids/chromatids separate during anaphase | also divides homologous chromosomes/homologous chromosomes separate during anaphase 1 and (sister) chromatids separate during anaphase 2 |
| h. | genetically identical | genetically different |
The image shows a cell from the root tip of an onion (Allium cepa) ( 2 n=16 ) during late prophase of mitosis.
How many chromatids are present in the cell?
8
16
32
64
C
What process occurs in both mitosis and meiosis?
Formation of chiasmata
Reduction division
Separation of chromatids
Exchange of alleles between non-sister chromatids
C
Describe what happens to the membranes of an animal cell during mitosis.
a nuclear membrane breaks down/disappears (in prophase/at start of mitosis)
b nuclear membrane reforms around two new nuclei (in telophase/at end of mitosis)
c plasma membrane pulled inwards at equator / cleavage furrow formed
d membrane pinches apart to form two cells / cytoplasm divided / cytokinesis
The following shows a micrograph.
How many cells are in metaphase?
2
3
5
7
B
The micrograph shows a plant cell of Lilium grandiflorum during meiosis.
Identify, giving reasons, the stage of meiosis shown by this cell.
a. anaphase II
b. as four daughter cells are being formed
OR
the centromeres split / sister chromatids separate
OR
sister chromatids/ chromosomes are pulled «by the spindle microtubules» to opposite poles
In a strain of soybeans, high oil content (H) in seeds is dominant to low oil content (h) and four seeds in a pod (F) is dominant to two seeds in a pod (f). A farmer crosses two soybean plants, both with high oil content and four seeds in a pod. The offspring have a phenotypic ratio of 9: 3: 3: 1.
The image shows the karyotype of a person who developed as a female.
Determine, with a reason, whether this karyotype shows that non-disjunction has occurred.
yes as there is only one X chromosome/chromosome missing/only 45 chromosomes
Hemophilia is a sex-linked disease that affected some members of royal families in Europe during the 19th and 20th centuries.
The diagram shows the structure of two chromosomes after the first division of meiosis, assuming that there was no crossing over or chiasmata formation.
Draw the same chromosomes to show their structure at the same stage of meiosis if there had been one chiasma between two gene loci.
All four upper arms with one A and both chromosomes with one B and one b on the lower arms.
official chromosome answer
State the stage of meiosis where chiasmata formation may occur.
prophase I;
The photomicrograph shows a section of onion (Allium cepa) root tip cells.
× 1000
Describe how a mitotic index could be obtained from this image.
a. count all cells in any stage of mitosis;
b. divide by total number of cells;
c. convert to percentage
OR
multiply by 100 ;
Marking guidance:
Do not accept other terms than cells.
Cadmium is a heavy metal that can cause environmental problems. Cadmium ions are released from various human activities such as the release of sewage sludge, mining and industrial processes. Plants take up cadmium ions and they enter food chains.
A study was carried out to look at the effect of various concentrations of cadmium ions on the mitotic index of the apical meristem of root cells from 4-day-old wheat (Triticum aestivum) seedlings.
State the effect of cadmium ion concentration on the mitotic index of root cells from wheat seedlings.
as concentration increases mitotic index decreases
OR
negative effect/correlation/relationship;
Suggest the effect the change in mitotic index would have on the wheat plant.
decreased growth/cell proliferation;
In which stage of the cell cycle are chromosomes duplicated?
G1 phase
G2 phase
S phase
Mitosis
C
Multicellular organisms benefit from cell specialization and division of labour.
Outline the processes occurring during interphase in the cell cycle.
growth/increase in cell size;
division of mitochondria/chloroplasts/production of more organelles/number of organelles doubled;
replication of DNA/amount of DNA is doubled;
transcription of genes/production of mRNA;
protein synthesis;
cell respiration/production of ATP;
Explain how the cell cycle is controlled.
a. cell cycle is a sequence of stages / cell cycle is G1, S,G2 and mitosis
b. (control of the cell cycle) by cyclins/cyclin
c. levels of cyclins rise (and fall)/fluctuate during the cell cycle/surge at different times/have to reach a certain concentration
d. conditions inside as well as outside the cell affect regulation
e. four cyclins/different cyclins to enter different stages of/events in the cell cycle / cyclins regulate the sequence/timing of the cell cycle/cyclins trigger the next stages
f. cyclin-dependent kinases / cyclins bind to kinases and activate them
g. kinases phosphorylate other proteins
h. phosphorylated proteins perform specific functions in the cell cycle
Many biological processes are cyclical. Examples of cycles can be found at the level of the cell, the organism and the ecosystem.
Explain how changes to the cell cycle can result in tumour formation.
cell cycle is (repeated) sequence of cytokinesis/cell division, (then) interphase (then) mitosis / cell cycle includes the sequence of interphase, mitosis and cytokinesis/cell division (to form new cells which repeat the cycle);
cyclins control/regulate this cycle / ensure the cell moves on to the next stage of the cycle when it is appropriate;
extra cells produced when they are needed;
tumour formation is the result of uncontrolled cell division/ cells growing and dividing endlessly;
repeated mitoses/high mitotic index;
due to mutations in oncogenes / oncogenes may become active and contribute to the development of a cancer cell;
carcinogens/radiation/mutagenic chemicals/mutagens/smoking cause mutations/tumours;
Which processes occur during the development of secondary tumours?
I. Cytokinesis
II. Metastasis
III. Mitosis
I and II only
II and III only
I and III only
I, II and III
D