IB Biology HL C1.1.16 Hl Feedback Inhibition Questions
Practise IB Biology HL 1.1.16 by applying feedback inhibition concepts to exam questions.
- Syllabus
- First assessment 2025
- Course
- Biology HL
- Level
- HL
Exam points
- Explain that an accumulated end product inhibits an earlier enzyme in its metabolic pathway through feedback inhibition.
- Identify end-product binding at an allosteric site and relate product concentration to slowing or stopping pathway output.
- Apply feedback inhibition to pathway examples such as isoleucine synthesis, including the regulated first step.
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IB Biology HL C1.1.16 Hl Feedback Inhibition Questions question 1
[Maximum number: 4]
Feedback mechanisms are used in living organisms both to promote and respond to change.
Explain the regulation of metabolic pathways by end-product inhibition.
final product in pathway acts as an inhibitor/blocks (reaction)/slows (reaction);
first/early/earlier enzyme (in pathway is inhibited);
non-competitive / binds at allosteric site / causes active site to change;
production of end-product reduced/paused when there is an excess;
isoleucine inhibits enzyme using threonine as substrate at start of pathway to isoleucine;
negative feedback / production restarts when end-product used up/concentration drops;
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