14. Coordination and response
- Syllabus
- 0610–2026–2027
- Section
- 14
- Level
- —

Electrical impulses travel along neurones.
A neurone is a nerve cell specialised to carry these electrical signals from one part of the nervous system to another.
The signal along a neurone is an electrical impulse; neurotransmitter molecules carry the signal across a synaptic gap, not along the neurone.
The mammalian nervous system has a central nervous system and a peripheral nervous system.
| Division | What it consists of |
|---|---|
| central nervous system (CNS) | brain and spinal cord |
| peripheral nervous system (PNS) | nerves outside the brain and spinal cord |
The spinal cord belongs to the CNS; nerves entering or leaving it belong to the PNS.
The nervous system coordinates and regulates body functions.
| Job | Meaning |
|---|---|
| receive information | receptors detect changes inside or outside the body |
| coordinate | the CNS integrates information and organises an appropriate response |
| regulate | impulses control effectors so body functions change when required |
Coordination links information to a response; regulation adjusts body functions. The nervous system does more than detect a stimulus.
Identify a neurone in a diagram by the direction and connections of its pathway, not only by its shape.
| Neurone | Direction of impulse | Diagram cue |
|---|---|---|
| sensory | receptor → CNS | enters the brain or spinal cord from a receptor |
| relay | within the CNS | links neurones inside the brain or spinal cord |
| motor | CNS → effector | leaves the brain or spinal cord for a muscle or gland |
Sensory neurones carry impulses towards the CNS; motor neurones carry them from the CNS. A relay neurone lies within the CNS.
A simple reflex arc is the pathway followed from detection of a stimulus to the action of an effector.
| Order | Component | Job |
|---|---|---|
| 1 | receptor | detects the stimulus |
| 2 | sensory neurone | carries an impulse to the CNS |
| 3 | relay neurone | passes the impulse within the CNS |
| 4 | motor neurone | carries an impulse away from the CNS |
| 5 | effector | produces the response |
receptor → sensory neurone → relay neurone → motor neurone → effector
A receptor detects the stimulus; an effector carries out the response. They are not types of neurone.
A reflex action automatically and rapidly coordinates a stimulus with the response of an effector.
| Feature | Meaning |
|---|---|
| automatic | occurs without conscious decision |
| rapid | the response follows the stimulus quickly |
| integrated and coordinated | nervous-system input is linked to a suitable output |
| effector response | a muscle contracts or a gland secretes |
A reflex action is the automatic response; a reflex arc is the nervous pathway that produces it. Effectors can be muscles or glands.
A synapse is a junction between two neurones.
The two neurones do not form one continuous cell: a small synaptic gap separates them, so the signal must cross the junction.
The synapse is the whole junction between neurones; the synaptic gap is only the space within that junction.
A synapse has different structures on the sending and receiving sides of a synaptic gap.
| Part | Position or contents |
|---|---|
| vesicles | in the end of the first neurone; contain neurotransmitter molecules |
| synaptic gap | small space between the two neurones |
| receptor proteins | in the membrane of the next neurone |
Vesicles contain neurotransmitter molecules; receptor proteins are on the next neurone and do not fill the gap.
Transmission across a synapse converts an arriving electrical impulse into a chemical signal and then stimulates a new electrical impulse.
| Order | Event |
|---|---|
| 1 | an impulse stimulates vesicles to release neurotransmitter molecules into the synaptic gap |
| 2 | neurotransmitter molecules diffuse across the gap |
| 3 | the molecules bind to receptor proteins on the next neurone |
| 4 | an impulse is stimulated in the next neurone |
Neurotransmitter diffuses only across the gap; the impulses travel along the neurones on either side.
Synapses ensure that impulses travel in one direction only.
| First neurone | Next neurone |
|---|---|
| has vesicles that release neurotransmitter | has receptor proteins that bind the neurotransmitter |
Because release machinery and matching receptors are on opposite sides, the signal passes from the first neurone to the next, not backwards across that synapse.
The one-way rule refers to transmission across a synapse; it is not caused by neurotransmitter diffusing in only one physical direction.
A sense organ is a group of receptor cells that responds to specific stimuli.
| Stimulus | Example sense organ |
|---|---|
| light | eye |
| sound | ear |
| touch or temperature | skin |
| chemicals | nose or tongue |
A sense organ contains receptor cells; it is not itself a stimulus, and different receptors respond to particular kinds of change.
Use position and connection to identify the seven required structures in an eye section.
| Structure | Identification cue |
|---|---|
| cornea | transparent curved front surface |
| iris | ring of tissue in front of the lens |
| pupil | opening in the centre of the iris |
| lens | transparent biconvex structure behind the pupil |
| retina | light-sensitive layer lining the back of the eye |
| optic nerve | bundle leaving the back of the eye |
| blind spot | point where the optic nerve leaves the retina |
The pupil is an opening, not a tissue. The blind spot is on the retina at the optic-nerve exit.
Each required eye structure has a distinct job in controlling, focusing, detecting or transmitting light information.
| Structure | Required function |
|---|---|
| cornea | refracts light |
| iris | controls how much light enters the pupil |
| pupil | opening through which light enters |
| lens | focuses light onto the retina |
| retina | contains light receptors, including receptors sensitive to different colours |
| optic nerve | carries impulses to the brain |
The cornea refracts incoming light and the lens focuses it; the retina detects light, while the optic nerve carries impulses rather than light.
The pupil reflex changes pupil diameter as light intensity changes.
| Light intensity | Pupil diameter | Effect |
|---|---|---|
| bright light | decreases; pupil constricts | less light enters |
| dim light | increases; pupil dilates | more light enters |
The pupil is the opening that changes diameter; the iris is the tissue that causes this change.
Circular and radial muscles in the iris act antagonistically: when one set contracts, the other relaxes.
| Condition | Circular muscles | Radial muscles | Pupil |
|---|---|---|---|
| bright light | contract | relax | constricts |
| dim light | relax | contract | dilates |
Both muscle sets do not contract together. Circular contraction narrows the pupil; radial contraction widens it.
Accommodation changes lens shape so light from objects at different distances is focused on the retina.
| Viewing | Ciliary muscles | Suspensory ligaments | Lens | Refraction |
|---|---|---|---|---|
| near object | contract | slacken; less tension | thicker, more convex | more |
| distant object | relax | tighten; more tension | thinner, less convex | less |
Near: ciliary muscles contract → ligaments slacken → lens becomes thicker → light is refracted more. Distant: every change reverses.
Ciliary-muscle contraction reduces tension in the suspensory ligaments; it does not pull the lens flatter.
Rods and cones are unevenly distributed across the retina.
| Retinal region | Rods | Cones |
|---|---|---|
| fovea | absent | highest concentration |
| peripheral retina | numerous | present in lower numbers |
| blind spot | absent | absent |
Overall, rods are more numerous across much of the retina, while cones form a sharp concentration at the fovea.
The blind spot has neither rods nor cones; the fovea has the highest cone concentration and no rods.
Rods and cones are light receptors with different sensitivities and visual roles.
| Receptor | Sensitivity and role |
|---|---|
| rods | more sensitive in low light; provide night vision |
| cones | three different kinds absorb light of different colours; provide colour vision |
Rods are more sensitive for dim-light vision but do not provide colour vision. Colour vision depends on three kinds of cone.
The fovea is a small region of the retina with the highest concentration of cone cells.
In an eye section, locate it on the retina opposite the lens and separate from the blind spot where the optic nerve exits.
The fovea provides the sharpest, most detailed colour vision because images of objects viewed directly are focused onto its densely packed cones.
The fovea is not the blind spot: the fovea is cone-rich, while the blind spot has no light receptors.
A hormone is a chemical substance produced by a gland, carried by the blood, and able to alter the activity of one or more specific target organs.
gland produces hormone → blood carries hormone → specific target organ changes activity
A hormone travels in the blood, but only target organs with the appropriate response are affected.
Identify each required endocrine gland by its position and match it to its named hormone.
| Endocrine gland | Position cue | Hormone |
|---|---|---|
| adrenal glands | on top of the kidneys | adrenaline |
| pancreas | across the upper abdomen | insulin |
| testes | male reproductive organs | testosterone |
| ovaries | female reproductive organs | oestrogen |
The adrenal glands sit above the kidneys but are separate glands; the pancreas secretes insulin, while glucagon is introduced separately in objective 14.3.5.
Adrenaline is secreted in fight-or-flight situations to prepare the body for rapid action.
| Effect | Change |
|---|---|
| breathing rate | increases |
| heart rate | increases |
| pupil diameter | increases |
For this objective, the required fight-or-flight effects are limited to increased breathing rate, increased heart rate and increased pupil diameter.
Nervous and hormonal control differ in speed of action and duration of effect.
| Control system | Speed of action | Duration of effect |
|---|---|---|
| nervous | fast | short-lived |
| hormonal | slower | longer-lasting |
A fast response is not necessarily long-lasting: nervous control is the faster but shorter-lived system.
Glucagon is secreted by the pancreas.
The pancreas is an endocrine gland that secretes both insulin and glucagon.
The pancreas secretes glucagon; the liver is a target organ in blood-glucose control but does not secrete glucagon.
Adrenaline prepares the body for increased metabolic activity by increasing blood glucose concentration and increasing heart rate.
| Adrenaline effect | Immediate value |
|---|---|
| increases blood glucose concentration | makes more glucose available for respiration |
| increases heart rate | circulates blood and glucose more rapidly |
The required metabolic-control effects here are increased blood glucose concentration and increased heart rate; detailed blood-glucose homeostasis belongs to the next Topic.
Homeostasis is the maintenance of a constant internal environment.
Internal conditions are kept within narrow limits so cells and enzymes can function effectively even when external conditions change.
Homeostasis keeps conditions within limits; it does not mean that every internal value is perfectly fixed.
Insulin decreases blood glucose concentration.
It is released when blood glucose concentration is too high and helps return the concentration towards its normal level.
Insulin lowers blood glucose concentration; glucagon raises it.
A set point is the normal level around which an internal condition is regulated. Negative feedback reverses a deviation from that set point.
| Stage | Job |
|---|---|
| 1 | a condition moves above or below its set point |
| 2 | receptors detect the change |
| 3 | a control system activates effectors |
| 4 | the response opposes the original change |
| 5 | the condition returns towards the set point |
Negative feedback opposes a change; it does not amplify the deviation from the set point.
The pancreas detects blood-glucose changes and uses insulin or glucagon to control the liver by negative feedback.
| Blood glucose | Pancreatic hormone | Liver response | Result |
|---|---|---|---|
| too high | more insulin | takes up glucose and converts glucose to glycogen | blood glucose falls |
| too low | more glucagon | converts glycogen to glucose and releases glucose | blood glucose rises |
The pancreas secretes the hormones; the liver stores or releases carbohydrate in response. Insulin and glucagon have opposite effects.
Type 1 diabetes is treated by replacing missing insulin and actively managing blood glucose concentration.
| Treatment action | Purpose |
|---|---|
| insulin injections or an insulin pump | supplies insulin |
| regular blood-glucose monitoring | guides insulin dose and detects unsafe levels |
| controlled carbohydrate intake and regular meals | limits large glucose changes |
| appropriate exercise | supports glucose control |
Insulin controls Type 1 diabetes but does not cure the destroyed insulin-producing cells.
Identify skin structures by both their shape and their connections.
| Structure | Identification cue |
|---|---|
| hair | shaft projecting through skin surface |
| hair erector muscle | sloping muscle attached to a hair follicle |
| sweat gland | coiled gland with a duct to the surface |
| receptor | sensory ending in the skin |
| sensory neurone | nerve fibre leading from a receptor |
| blood vessels | tubes and capillary networks in the skin |
| fatty tissue | layer of large fat cells beneath the skin |
A sweat gland is a coiled secretory structure; a receptor detects change, while its sensory neurone carries impulses.
The brain coordinates responses that balance heat loss and heat production around normal body temperature.
| Condition | Response | Effect |
|---|---|---|
| too hot | sweating | evaporation removes heat |
| too cold | shivering | muscle contraction releases heat |
| cold surroundings | hairs raised and fatty tissue insulates | trapped air and fat reduce heat loss |
Temperature receptors provide information to the brain, which coordinates the appropriate effectors.
Sweating cools only when sweat evaporates; shivering generates heat through repeated muscle contractions.
Arterioles supplying skin-surface capillaries change diameter to alter heat transfer from the blood.
| Condition | Arterioles | Blood near skin surface | Heat loss |
|---|---|---|---|
| too hot | vasodilate | more | increases |
| too cold | vasoconstrict | less | decreases |
Vasodilation and vasoconstriction describe changes in arteriole diameter, not capillaries moving closer to or farther from the skin.
Gravitropism is a growth response in which part of a plant grows towards or away from gravity.
| Response | Direction | Typical example |
|---|---|---|
| positive gravitropism | towards gravity | roots grow downwards |
| negative gravitropism | away from gravity | shoots grow upwards |
Gravitropism is directional growth in response to gravity, not simply any downward or upward movement.
Phototropism is a growth response in which part of a plant grows towards or away from the direction of a light source.
| Response | Direction | Typical example |
|---|---|---|
| positive phototropism | towards light | shoots grow towards a one-sided light source |
| negative phototropism | away from light | roots may grow away from light |
Phototropism is directional growth caused by the direction of light; photosynthesis uses light but is not a tropic response.
A tropism investigation changes one directional stimulus and records the direction of root and shoot growth.
| Organ | Gravity response | Light response |
|---|---|---|
| root | grows towards gravity | commonly grows away from light |
| shoot | grows away from gravity | grows towards light |
| Design feature | Purpose |
|---|---|
| germinating seedlings of similar age | comparable starting material |
| one-sided light or darkness | isolate light direction |
| horizontal placement or clinostat control | test or cancel a constant gravity direction |
| keep water, temperature and time constant | fair comparison |
| record starting and final root/shoot directions | describe the growth response |
A clinostat rotates seedlings so gravity does not act continuously on one side; it is a control for directional gravity, not a source of light.
Phototropism and gravitropism of shoots are chemical growth responses controlled by auxin.
directional stimulus → unequal auxin distribution → unequal cell elongation on opposite sides → shoot curves
In a shoot, the side with more auxin elongates more, so the unequal growth produces curvature towards light or away from gravity.
The shoot bends because its two sides elongate at different rates, not because mature cells move from one side to the other.
Auxin is made in the shoot tip and controls curvature by changing cell elongation below the tip.
| Order | Event |
|---|---|
| 1 | auxin is made in the shoot tip |
| 2 | auxin diffuses through the plant away from the tip |
| 3 | light or gravity causes auxin to become unequally distributed |
| 4 | auxin stimulates cell elongation in the shoot |
| 5 | cells on the side with more auxin elongate more, so the shoot bends |
With light from one side, more auxin accumulates on the shaded side; greater elongation there bends the shoot towards the light.
Auxin is produced in the shoot tip but acts on elongating cells below it; it stimulates cell elongation rather than cell movement.