14. Coordination and response

Syllabus
0610–2026–2027
Section
14
Level
—

14.1 Coordination and response

Syllabus
0610–2026–2027
Topic
14.1
Level
—

State how nerve signals travel

Electrical impulses travel along neurones.

A neurone is a nerve cell specialised to carry these electrical signals from one part of the nervous system to another.

The signal along a neurone is an electrical impulse; neurotransmitter molecules carry the signal across a synaptic gap, not along the neurone.

Describe the mammalian nervous system

The mammalian nervous system has a central nervous system and a peripheral nervous system.

Division What it consists of
central nervous system (CNS) brain and spinal cord
peripheral nervous system (PNS) nerves outside the brain and spinal cord

The spinal cord belongs to the CNS; nerves entering or leaving it belong to the PNS.

Describe the role of the nervous system

The nervous system coordinates and regulates body functions.

Job Meaning
receive information receptors detect changes inside or outside the body
coordinate the CNS integrates information and organises an appropriate response
regulate impulses control effectors so body functions change when required

Coordination links information to a response; regulation adjusts body functions. The nervous system does more than detect a stimulus.

Identify sensory, relay and motor neurones

Identify a neurone in a diagram by the direction and connections of its pathway, not only by its shape.

Neurone Direction of impulse Diagram cue
sensory receptor → CNS enters the brain or spinal cord from a receptor
relay within the CNS links neurones inside the brain or spinal cord
motor CNS → effector leaves the brain or spinal cord for a muscle or gland

Sensory neurones carry impulses towards the CNS; motor neurones carry them from the CNS. A relay neurone lies within the CNS.

Describe a simple reflex arc

A simple reflex arc is the pathway followed from detection of a stimulus to the action of an effector.

Order Component Job
1 receptor detects the stimulus
2 sensory neurone carries an impulse to the CNS
3 relay neurone passes the impulse within the CNS
4 motor neurone carries an impulse away from the CNS
5 effector produces the response

receptor → sensory neurone → relay neurone → motor neurone → effector

A receptor detects the stimulus; an effector carries out the response. They are not types of neurone.

Describe a reflex action

A reflex action automatically and rapidly coordinates a stimulus with the response of an effector.

Feature Meaning
automatic occurs without conscious decision
rapid the response follows the stimulus quickly
integrated and coordinated nervous-system input is linked to a suitable output
effector response a muscle contracts or a gland secretes

A reflex action is the automatic response; a reflex arc is the nervous pathway that produces it. Effectors can be muscles or glands.

Define a synapse

A synapse is a junction between two neurones.

The two neurones do not form one continuous cell: a small synaptic gap separates them, so the signal must cross the junction.

The synapse is the whole junction between neurones; the synaptic gap is only the space within that junction.

Describe the structure of a synapse

A synapse has different structures on the sending and receiving sides of a synaptic gap.

Part Position or contents
vesicles in the end of the first neurone; contain neurotransmitter molecules
synaptic gap small space between the two neurones
receptor proteins in the membrane of the next neurone

Vesicles contain neurotransmitter molecules; receptor proteins are on the next neurone and do not fill the gap.

Describe transmission across a synapse

Transmission across a synapse converts an arriving electrical impulse into a chemical signal and then stimulates a new electrical impulse.

Order Event
1 an impulse stimulates vesicles to release neurotransmitter molecules into the synaptic gap
2 neurotransmitter molecules diffuse across the gap
3 the molecules bind to receptor proteins on the next neurone
4 an impulse is stimulated in the next neurone

Neurotransmitter diffuses only across the gap; the impulses travel along the neurones on either side.

State why synaptic transmission is one-way

Synapses ensure that impulses travel in one direction only.

First neurone Next neurone
has vesicles that release neurotransmitter has receptor proteins that bind the neurotransmitter

Because release machinery and matching receptors are on opposite sides, the signal passes from the first neurone to the next, not backwards across that synapse.

The one-way rule refers to transmission across a synapse; it is not caused by neurotransmitter diffusing in only one physical direction.

14.2 Sense organs

Syllabus
0610–2026–2027
Topic
14.2
Level
—

Describe sense organs

A sense organ is a group of receptor cells that responds to specific stimuli.

Stimulus Example sense organ
light eye
sound ear
touch or temperature skin
chemicals nose or tongue

A sense organ contains receptor cells; it is not itself a stimulus, and different receptors respond to particular kinds of change.

Identify the required structures of the eye

Use position and connection to identify the seven required structures in an eye section.

Structure Identification cue
cornea transparent curved front surface
iris ring of tissue in front of the lens
pupil opening in the centre of the iris
lens transparent biconvex structure behind the pupil
retina light-sensitive layer lining the back of the eye
optic nerve bundle leaving the back of the eye
blind spot point where the optic nerve leaves the retina

The pupil is an opening, not a tissue. The blind spot is on the retina at the optic-nerve exit.

Describe the functions of the eye structures

Each required eye structure has a distinct job in controlling, focusing, detecting or transmitting light information.

Structure Required function
cornea refracts light
iris controls how much light enters the pupil
pupil opening through which light enters
lens focuses light onto the retina
retina contains light receptors, including receptors sensitive to different colours
optic nerve carries impulses to the brain

The cornea refracts incoming light and the lens focuses it; the retina detects light, while the optic nerve carries impulses rather than light.

Explain the pupil reflex using light intensity

The pupil reflex changes pupil diameter as light intensity changes.

Light intensity Pupil diameter Effect
bright light decreases; pupil constricts less light enters
dim light increases; pupil dilates more light enters

The pupil is the opening that changes diameter; the iris is the tissue that causes this change.

Explain antagonistic action in the pupil reflex

Circular and radial muscles in the iris act antagonistically: when one set contracts, the other relaxes.

Condition Circular muscles Radial muscles Pupil
bright light contract relax constricts
dim light relax contract dilates

Both muscle sets do not contract together. Circular contraction narrows the pupil; radial contraction widens it.

Explain accommodation for near and distant objects

Accommodation changes lens shape so light from objects at different distances is focused on the retina.

Viewing Ciliary muscles Suspensory ligaments Lens Refraction
near object contract slacken; less tension thicker, more convex more
distant object relax tighten; more tension thinner, less convex less

Near: ciliary muscles contract → ligaments slacken → lens becomes thicker → light is refracted more. Distant: every change reverses.

Ciliary-muscle contraction reduces tension in the suspensory ligaments; it does not pull the lens flatter.

Describe the distribution of rods and cones

Rods and cones are unevenly distributed across the retina.

Retinal region Rods Cones
fovea absent highest concentration
peripheral retina numerous present in lower numbers
blind spot absent absent

Overall, rods are more numerous across much of the retina, while cones form a sharp concentration at the fovea.

The blind spot has neither rods nor cones; the fovea has the highest cone concentration and no rods.

Outline the functions of rods and cones

Rods and cones are light receptors with different sensitivities and visual roles.

Receptor Sensitivity and role
rods more sensitive in low light; provide night vision
cones three different kinds absorb light of different colours; provide colour vision

Rods are more sensitive for dim-light vision but do not provide colour vision. Colour vision depends on three kinds of cone.

Identify the fovea and state its function

The fovea is a small region of the retina with the highest concentration of cone cells.

In an eye section, locate it on the retina opposite the lens and separate from the blind spot where the optic nerve exits.

The fovea provides the sharpest, most detailed colour vision because images of objects viewed directly are focused onto its densely packed cones.

The fovea is not the blind spot: the fovea is cone-rich, while the blind spot has no light receptors.

14.3 Hormones

Syllabus
0610–2026–2027
Topic
14.3
Level
—

Define a hormone

A hormone is a chemical substance produced by a gland, carried by the blood, and able to alter the activity of one or more specific target organs.

gland produces hormone → blood carries hormone → specific target organ changes activity

A hormone travels in the blood, but only target organs with the appropriate response are affected.

Match endocrine glands to their hormones

Identify each required endocrine gland by its position and match it to its named hormone.

Endocrine gland Position cue Hormone
adrenal glands on top of the kidneys adrenaline
pancreas across the upper abdomen insulin
testes male reproductive organs testosterone
ovaries female reproductive organs oestrogen

The adrenal glands sit above the kidneys but are separate glands; the pancreas secretes insulin, while glucagon is introduced separately in objective 14.3.5.

Describe adrenaline in fight-or-flight situations

Adrenaline is secreted in fight-or-flight situations to prepare the body for rapid action.

Effect Change
breathing rate increases
heart rate increases
pupil diameter increases

For this objective, the required fight-or-flight effects are limited to increased breathing rate, increased heart rate and increased pupil diameter.

Compare nervous and hormonal control

Nervous and hormonal control differ in speed of action and duration of effect.

Control system Speed of action Duration of effect
nervous fast short-lived
hormonal slower longer-lasting

A fast response is not necessarily long-lasting: nervous control is the faster but shorter-lived system.

State where glucagon is secreted

Glucagon is secreted by the pancreas.

The pancreas is an endocrine gland that secretes both insulin and glucagon.

The pancreas secretes glucagon; the liver is a target organ in blood-glucose control but does not secrete glucagon.

Describe the metabolic effects of adrenaline

Adrenaline prepares the body for increased metabolic activity by increasing blood glucose concentration and increasing heart rate.

Adrenaline effect Immediate value
increases blood glucose concentration makes more glucose available for respiration
increases heart rate circulates blood and glucose more rapidly

The required metabolic-control effects here are increased blood glucose concentration and increased heart rate; detailed blood-glucose homeostasis belongs to the next Topic.

14.4 Homeostasis

Syllabus
0610–2026–2027
Topic
14.4
Level
—

Define homeostasis

Homeostasis is the maintenance of a constant internal environment.

Internal conditions are kept within narrow limits so cells and enzymes can function effectively even when external conditions change.

Homeostasis keeps conditions within limits; it does not mean that every internal value is perfectly fixed.

State the effect of insulin

Insulin decreases blood glucose concentration.

It is released when blood glucose concentration is too high and helps return the concentration towards its normal level.

Insulin lowers blood glucose concentration; glucagon raises it.

Explain negative feedback and a set point

A set point is the normal level around which an internal condition is regulated. Negative feedback reverses a deviation from that set point.

Stage Job
1 a condition moves above or below its set point
2 receptors detect the change
3 a control system activates effectors
4 the response opposes the original change
5 the condition returns towards the set point

Negative feedback opposes a change; it does not amplify the deviation from the set point.

Explain control of blood glucose concentration

The pancreas detects blood-glucose changes and uses insulin or glucagon to control the liver by negative feedback.

Blood glucose Pancreatic hormone Liver response Result
too high more insulin takes up glucose and converts glucose to glycogen blood glucose falls
too low more glucagon converts glycogen to glucose and releases glucose blood glucose rises

The pancreas secretes the hormones; the liver stores or releases carbohydrate in response. Insulin and glucagon have opposite effects.

Outline treatment of Type 1 diabetes

Type 1 diabetes is treated by replacing missing insulin and actively managing blood glucose concentration.

Treatment action Purpose
insulin injections or an insulin pump supplies insulin
regular blood-glucose monitoring guides insulin dose and detects unsafe levels
controlled carbohydrate intake and regular meals limits large glucose changes
appropriate exercise supports glucose control

Insulin controls Type 1 diabetes but does not cure the destroyed insulin-producing cells.

Identify the required structures in skin

Identify skin structures by both their shape and their connections.

Structure Identification cue
hair shaft projecting through skin surface
hair erector muscle sloping muscle attached to a hair follicle
sweat gland coiled gland with a duct to the surface
receptor sensory ending in the skin
sensory neurone nerve fibre leading from a receptor
blood vessels tubes and capillary networks in the skin
fatty tissue layer of large fat cells beneath the skin

A sweat gland is a coiled secretory structure; a receptor detects change, while its sensory neurone carries impulses.

Explain maintenance of body temperature

The brain coordinates responses that balance heat loss and heat production around normal body temperature.

Condition Response Effect
too hot sweating evaporation removes heat
too cold shivering muscle contraction releases heat
cold surroundings hairs raised and fatty tissue insulates trapped air and fat reduce heat loss

Temperature receptors provide information to the brain, which coordinates the appropriate effectors.

Sweating cools only when sweat evaporates; shivering generates heat through repeated muscle contractions.

Explain vasodilation and vasoconstriction

Arterioles supplying skin-surface capillaries change diameter to alter heat transfer from the blood.

Condition Arterioles Blood near skin surface Heat loss
too hot vasodilate more increases
too cold vasoconstrict less decreases

Vasodilation and vasoconstriction describe changes in arteriole diameter, not capillaries moving closer to or farther from the skin.

14.5 Tropic responses

Syllabus
0610–2026–2027
Topic
14.5
Level
—

Define gravitropism

Gravitropism is a growth response in which part of a plant grows towards or away from gravity.

Response Direction Typical example
positive gravitropism towards gravity roots grow downwards
negative gravitropism away from gravity shoots grow upwards

Gravitropism is directional growth in response to gravity, not simply any downward or upward movement.

Define phototropism

Phototropism is a growth response in which part of a plant grows towards or away from the direction of a light source.

Response Direction Typical example
positive phototropism towards light shoots grow towards a one-sided light source
negative phototropism away from light roots may grow away from light

Phototropism is directional growth caused by the direction of light; photosynthesis uses light but is not a tropic response.

Investigate tropic responses in roots and shoots

A tropism investigation changes one directional stimulus and records the direction of root and shoot growth.

Organ Gravity response Light response
root grows towards gravity commonly grows away from light
shoot grows away from gravity grows towards light
Design feature Purpose
germinating seedlings of similar age comparable starting material
one-sided light or darkness isolate light direction
horizontal placement or clinostat control test or cancel a constant gravity direction
keep water, temperature and time constant fair comparison
record starting and final root/shoot directions describe the growth response

A clinostat rotates seedlings so gravity does not act continuously on one side; it is a control for directional gravity, not a source of light.

Explain tropisms as chemical control of shoot growth

Phototropism and gravitropism of shoots are chemical growth responses controlled by auxin.

directional stimulus → unequal auxin distribution → unequal cell elongation on opposite sides → shoot curves

In a shoot, the side with more auxin elongates more, so the unequal growth produces curvature towards light or away from gravity.

The shoot bends because its two sides elongate at different rates, not because mature cells move from one side to the other.

Explain how auxin controls shoot growth

Auxin is made in the shoot tip and controls curvature by changing cell elongation below the tip.

Order Event
1 auxin is made in the shoot tip
2 auxin diffuses through the plant away from the tip
3 light or gravity causes auxin to become unequally distributed
4 auxin stimulates cell elongation in the shoot
5 cells on the side with more auxin elongate more, so the shoot bends

With light from one side, more auxin accumulates on the shaded side; greater elongation there bends the shoot towards the light.

Auxin is produced in the shoot tip but acts on elongating cells below it; it stimulates cell elongation rather than cell movement.