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IB Biology SL D2.1.10 Down Syndrome Questions

Analyse how failed chromosome separation creates abnormal gametes and can produce Down syndrome in IB Biology SL D2.1.10.

Syllabus
First assessment 2025
Course
Biology SL
Level
SL

Exam points

  • Explain how non-disjunction during meiosis produces gametes with abnormal chromosome numbers and can cause trisomy 21.
  • Identify or interpret trisomy, abnormal gamete chromosome counts and Down-syndrome karyotype evidence.
  • Interpret maternal-age incidence evidence for chromosome-21 non-disjunction and trisomy.

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Study D2.1.10—Down syndrome conceptsOpen the corresponding Concept lesson for explanations, examples and exam connections.

IB Biology SL D2.1.10 Down Syndrome Questions question 1

[Maximum number: 2]

The following sequence of pictures, made using an electronic imaging technique, shows a cell undergoing division.

Image I

Image I

Explain, using one example, how non-disjunction in meiosis can lead to changes in chromosome number.

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