IB Biology SL D Continuity & Change Question Bank
Practise IB Biology SL D Continuity and Change through questions on genes, inheritance, evolution and biodiversity change.
- Syllabus
- First assessment 2025
- Course
- Biology SL
- Level
- SL
Practise IB Biology SL D Continuity and Change through questions on genes, inheritance, evolution and biodiversity change.
What is required to replicate DNA?
Temperature of 37∘C
Free nucleotides carrying A, C, G and T bases
Plasmids
Endonuclease
B
Mitosis produces genetically identical cells, which become specialized by expressing specific genes. This ensures that tissues and organs are adapted to their functions.
Outline how the behaviour of chromosomes during mitosis ensures the production of genetically identical cells.
a. each/one chromosome consists of (two genetically) identical chromatids
OR
sister chromatids are (genetically) identical
OR
replication (in interphase/S phase) produces two (genetically) identical DNA strands
OR
diploid cells contain two (genetically) identical copies of DNA;
b. (DNA) condense/coil (in prophase) to form chromosomes
OR
(chromosomes/chromatids) attach to spindle fibres (in metaphase)
OR
(chromosomes/chromatids) align/place in the center/equator of the cell (in metaphase);
c. microtubules contract/shorten
OR
(chromatids/chromosomes) are separated/pulled apart (in anaphase);
d. (chromatids/chromosomes) move to/reach poles/ends of cell (in telophase)
OR
one (copy of each identical) chromatid/chromosome in each new/daughter cell;
4
Marking guidance:
max
Describe how mRNA is produced in the nucleus.
a. RNA polymerase unwinds/unzips DNA / breaks hydrogen bonds;
b. (DNA) template/antisense strand is used;
c. (free) RNA nucleotides added (to DNA);
d. (by) complementary base pairing / A-U AND G-C;
e. RNA polymerase joins/attaches (RNA) nucleotides (on new mRNA strand)/forms (phosphodiester) bonds;
f. RNA polymerase/mRNA strand detaches/DNA strands reattach OR
RNA polymerase reach the stop codon;
4
Marking guidance:
max
Psammonobiotus balticus belongs to a group of protists (unicellular eukaryotic organisms) that have a shell surrounding most of the cell, which provides shelter from predators. The graph shows the frequency of varying shell lengths in a population of P. balticus.

Mutations may increase variation within a species. Compare and contrast substitution and insertion mutations.
Similarity:
a. both involve changes in the sequence of DNA/bases/nucleotides/triplets
OR
both may cause the production of a different amino acid/protein/polypeptide;
Difference:
b. substitution changes a base/nucleotide while insertion adds a base/nucleotide
OR
substitution changes one triplet while insertion changes more / causes frameshift
OR
substitution may not change protein/polypeptide function while insertion usually does;
Marking guidance:
Accept codon in place of triplet.
b. the contrast between substitution and insertion must be clear.
2
max
Which process contributes to growth of a multicellular body?
Exocytosis
Meiosis
Mitosis
Osmosis
C