IB Biology SL C2.2 Neural Signalling Questions
Practise IB Biology SL C2.2 by linking neuron structure, resting potential, myelin and impulse conduction to exam evidence.
- Syllabus
- First assessment 2025
- Course
- Biology SL
- Level
- SL
Practise IB Biology SL C2.2 by linking neuron structure, resting potential, myelin and impulse conduction to exam evidence.
The diagram below shows a motor neuron.
Label the structures indicated by the numbers I-IV.
| I | nucleus/cell body/soma |
| II | myelin sheath/Schwann cell |
| III | axon |
| IV | dendrites |
Define resting potential.
the neuron/membrane is not conducting an impulse/message/signal / inside of cell/neuron has a (net) negative charge/ -70 mV compared to outside / outside of cell/neuron is positive relative to inside
Outline how nerve impulses are transmitted along a nerve fibre.
a. (sodium channels/voltage-gated channels open and) Na+ diffuse into neuron (down concentration gradient);
b. inside of neuron becomes positive compared to outside / potential is reversed / depolarization;
c. wave of depolarization moves (down the membrane);
d. (potassium channels open and) K+ diffuse out (down concentration gradient);
e. inside becomes negative compared with outside / potential across membrane restored / repolarization;
f. active transport of K+ (into neuron) and Na+ (out of neuron) restores resting potential;
Scientists used MRI to calculate the speed of transmission of nerve impulses along axons of brain neurons.
Describe the relationship between speed of transmission and axon diameter.
as axon diameter increases, the speed of transmission increases too / positive
correlation/relationship;
The electron micrograph shows part of a synapse between two neurons.
Deduce what type of substance the vesicles contain.
neurotransmitter/acetylcholine/another verified example of neurotransmitter;
Distinguish between the presynaptic and postsynaptic membranes by giving two differences.
a. (only) pre-synaptic membrane has calcium channels/allows calcium to diffuse across
OR (only) pre-synaptic membrane releases neurotransmitters from their axon terminals;
b. (only) post-synaptic membrane has receptors for neurotransmitter OR (only) accept neurotransmitter in their dendrites/post-synaptic membrane;
c. the presynaptic membrane is at the axon terminal, but the post synaptic membrane is at a dendrite;
Marking guidance:
Accept other verified differences.
The gap between the presynaptic and postsynaptic membranes is very narrow. Suggest an advantage of this.
short distance for diffusion of neurotransmitter;
synaptic transmission is faster;
The diagram below shows a motor neuron.
Label the structures indicated by the numbers I-IV.
| I | nucleus/cell body/soma |
| II | myelin sheath/Schwann cell |
| III | axon |
| IV | dendrites |
The diagram below shows a motor neuron.
Define resting potential.
the neuron/membrane is not conducting an impulse/message/signal / inside of cell/neuron has a (net) negative charge/ -70 mV compared to outside / outside of cell/neuron is positive relative to inside
The diagram below shows a motor neuron.
Outline how nerve impulses are transmitted along a nerve fibre.
a. (sodium channels/voltage-gated channels open and) Na+ diffuse into neuron (down concentration gradient);
b. inside of neuron becomes positive compared to outside / potential is reversed / depolarization;
c. wave of depolarization moves (down the membrane);
d. (potassium channels open and) K+ diffuse out (down concentration gradient);
e. inside becomes negative compared with outside / potential across membrane restored / repolarization;
f. active transport of K+ (into neuron) and Na+ (out of neuron) restores resting potential;
The neuron is a specialized cell that exhibits a structure important to its function.
The diagram shows a neuron interacting with a muscle cell.
Describe how neurotransmitters are released from a presynaptic neuron membrane.
a. action potential/nerve impulse reaches the end of the presynaptic neuron;
b. impulse/action potential/depolarization of the (presynaptic) membrane causes calcium (ions)/ Ca2+ uptake/diffusion into the neuron;
c. (calcium ions) cause vesicles to move to the (presynaptic) membrane;
d. vesicles contain neurotransmitter;
e. neurotransmitter released into the synaptic gap/cleft by exocytosis/when vesicle fuses with membrane;
The diagram shows a neuron.
Describe how an excitatory postsynaptic potential is generated.
Up to one additional mark is available for the construction of your answer.
a. calcium/ Ca2+/Ca moves into the presynaptic membrane
OR
neurotransmitter/acetylcholine released from presynaptic membrane;
b. (neurotransmitter) diffuses across the synapse/synaptic cleft;
c. binds to transmembrane receptors/receptors in postsynaptic membrane;
d. (protein) channels open/ Na+ /positive ions diffuse in;
e. causes depolarization (of (post synaptic) membrane) / action potential / membrane potential increases;