IB Biology SL C2.2 Neural Signalling Questions

Practise IB Biology SL C2.2 by linking neuron structure, resting potential, myelin and impulse conduction to exam evidence.

Syllabus
First assessment 2025
Course
Biology SL
Level
SL

Exam points

  • Label neuron structures and distinguish sensory, relay and motor neuron roles, directions and connections.
  • Define resting potential, read its approximate negative voltage, and explain the ATP-driven pump moving 3 Na⁺ out for 2 K⁺ in.
  • Trace nerve impulses through threshold, Na⁺ influx/depolarization and K⁺ efflux/repolarization, using membrane-potential diagrams.
  • Relate axon diameter and myelin sheath to faster impulse transmission and saltatory conduction.
  • Distinguish presynaptic release sites from postsynaptic receptors and explain how the narrow cleft supports rapid diffusion.
  • Explain one-way synaptic transmission from action-potential/Ca²⁺-triggered vesicle release through cleft diffusion to postsynaptic receptor activation.
  • Explain how neurotransmitter binding opens postsynaptic ion channels to generate an EPSP and make threshold more likely.

Question 1

[Maximum number: 6]

The diagram below shows a motor neuron.

Motor-neuron drawing ending on muscle fibres. I points to the dark oval in the cell body, II to the long central fibre, III to a segmented covering and IV to branches extending from the cell body. Blank label lines accompany I–IV.

Question (a)

(a)

Label the structures indicated by the numbers I-IV.

[ 2 ]

Question (b)

(b)

Define resting potential.

[ 1 ]

Question (c)

(c)

Outline how nerve impulses are transmitted along a nerve fibre.

[ 3 ]

Question 2

[Maximum number: 1]

Scientists used MRI to calculate the speed of transmission of nerve impulses along axons of brain neurons.

Figure for Question 2 — IB Biology SL

Describe the relationship between speed of transmission and axon diameter.

Question 3

[Maximum number: 4]

The electron micrograph shows part of a synapse between two neurons.

Figure for Question 3 — IB Biology SL

Question (a)

(a)

Deduce what type of substance the vesicles contain.

[ 1 ]

Question (b)

(b)

Distinguish between the presynaptic and postsynaptic membranes by giving two differences.

[ 2 ]

Question (c)

(c)

The gap between the presynaptic and postsynaptic membranes is very narrow. Suggest an advantage of this.

[ 1 ]

Question 4

[Maximum number: 2]

The diagram below shows a motor neuron.

Motor-neuron drawing ending on muscle fibres. I points to the dark oval in the cell body, II to the long central fibre, III to a segmented covering and IV to branches extending from the cell body. Blank label lines accompany I–IV.

Label the structures indicated by the numbers I-IV.

Question 5

[Maximum number: 1]

The diagram below shows a motor neuron.

Motor-neuron drawing ending on muscle fibres. I points to the dark oval in the cell body, II to the long central fibre, III to a segmented covering and IV to branches extending from the cell body. Blank label lines accompany I–IV.

Define resting potential.

Question 6

[Maximum number: 3]

The diagram below shows a motor neuron.

Motor-neuron drawing ending on muscle fibres. I points to the dark oval in the cell body, II to the long central fibre, III to a segmented covering and IV to branches extending from the cell body. Blank label lines accompany I–IV.

Outline how nerve impulses are transmitted along a nerve fibre.

Question 7

[Maximum number: 3]

The neuron is a specialized cell that exhibits a structure important to its function.

The diagram shows a neuron interacting with a muscle cell.

Figure for Question 7 — IB Biology SL

Describe how neurotransmitters are released from a presynaptic neuron membrane.

Question 8

[Maximum number: 3]

The diagram shows a neuron.

Figure for Question 8 — IB Biology SL

Describe how an excitatory postsynaptic potential is generated.

Up to one additional mark is available for the construction of your answer.

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