Question 1
The diagram shows a G protein, bound to a G protein-coupled receptor (GPCR), a transmembrane receptor which responds to epinephrine (adrenaline).
Explain how epinephrine exerts its effects in the cell.
The diagram shows a G protein, bound to a G protein-coupled receptor (GPCR), a transmembrane receptor which responds to epinephrine (adrenaline).
Explain how epinephrine exerts its effects in the cell.
a. epinephrine is a ligand / binds to (GPCR) receptors in cell membrane;
b. triggers G-protein activation / triggers G protein phosphorylation;
c. initiates a cascade of events producing cAMP / adenylyl cyclase enzymes stimulates cAMP synthesis;
d. (cAMP) acts as a second messenger;
e. signals/influences/mediates specific cellular responses;
Marking guidance:
Accept cyclic AMP for cAMP.
3
max