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B1.1.7—Glycoproteins in cell-cell recognition

Glycoproteins and glycolipids display carbohydrate chains at the cell surface, enabling recognition, adhesion, signalling, and immune compatibility between neighbouring cells.

Syllabus
First assessment 2025
Objective
B1.1.7
Level
HL

Structure To Function

B1.1 becomes easy when every answer follows structure -> property -> function. Carbon skeletons and functional groups create molecular diversity. Condensation builds larger molecules and hydrolysis breaks them. Alpha-glucose stores energy as starch and glycogen; beta-glucose forms strong cellulose. Surface carbohydrates enable recognition. Lipids are hydrophobic, triglycerides store energy, phospholipids self-assemble into bilayers, and steroids cross membranes because they are mostly non-polar.

  • Carbon bonding and functional groups explain molecular diversity.
  • Condensation releases water; hydrolysis uses water.
  • Carbohydrates can store energy, build cell walls, and mark cell surfaces.
  • Lipids are hydrophobic and not true polymers.
  • Triglycerides store energy; phospholipids form membranes; steroids signal across membranes.

Concept essentials

  • Glycoproteins are proteins with attached carbohydrate chains.
  • Glycolipids are lipids with attached carbohydrate chains.
  • Cell-surface carbohydrates can act as recognition markers.
  • ABO blood group antigens depend on surface carbohydrate differences.
ConceptIB Biology HL