A3.1.6—Diversity in chromosome numbers

Chromosome numbers are usually constant within a species but vary widely between species without measuring complexity, evolutionary progress, or organism type.

Syllabus
First assessment 2025
Objective
A3.1.6
Level
HL

Exam analysis

Chance of appearing2%of analysed past papers
Latest appearanceMay 2022
Most common paperPaper1
Typical marks1

Common command terms

  • State

Scoring notes

Common mistake
Treating chromosome number as a measure of organism complexity or evolutionary progress.

Recent exam appearances

May 2022Paper1 ["HL"] · TZ111[ 1 ]A3.1.6—Diversity in chromosome numbers
November 2016Paper1 ["HL"] · TZ012[ 1 ]A3.1.6—Diversity in chromosome numbers
Practice this objective

Coverage 2016–2022 · Updated 15 Jul 2026

Read Chromosome Number and Karyograms as Evidence

A clean chromosome-number comparison above a human karyogram with chromosome 2 fusion highlighted and labeled by length, banding pattern, and centromere position.

Chromosome number is usually constant within a species but varies widely between species. Humans have 46 chromosomes and chimpanzees have 48; diploid chromosome numbers are normally even because chromosomes occur as homologous pairs.

Karyotyping records the number and structural appearance of chromosomes. A karyogram is the ordered image produced by pairing homologous chromosomes and arranging them using length, banding pattern and centromere position.

A karyogram can reveal chromosome-number differences and structural similarities. Evidence for human chromosome 2 fusion includes its correspondence to two ancestral ape chromosomes, internal telomeric sequences at the predicted fusion site and remnants of a second centromere.

When pairing chromosomes in a karyogram, first match banding patterns, then confirm comparable length and centromere position rather than relying on size alone.

The observations support a testable fusion hypothesis; they should not be described as proof based only on humans having two fewer chromosomes than chimpanzees.

Diversity in chromosome numbers

Assessment in practice

1 marks
How it is assessed

This objective is assessed through structured response, commonly using State.

Command terms

State

What earns marks

Build the answer around this relationship: Diploid chromosome number is usually constant within a species.

Watch for

Treating chromosome number as a measure of organism complexity or evolutionary progress.

Representative question

Question 1

[Maximum number: 1]

State the chromosome number in this gorilla.

SL Transfer: Classify With Evidence

For SL, A3.1 is really one evidence map. Variation explains why individuals differ. Morphology and binomial nomenclature help group and name organisms. The biological species concept uses interbreeding and fertile offspring, but boundaries can be difficult during gradual speciation. Chromosomes and karyograms add cellular evidence. Genomes, SNPs, genome size, and whole genome sequencing add molecular evidence. The skill is choosing the right evidence for the question.

  • Variation supports natural selection.
  • Morphology groups by structure; binomial nomenclature names species universally.
  • Biological species concept uses interbreeding and fertile offspring.
  • Karyograms compare chromosome number and structure.
  • Genome evidence includes SNPs, between-species differences, genome size, and sequencing uses.

Concept essentials

  • Diploid chromosome number is usually constant within a species.
  • Haploid cells contain one chromosome from each homologous pair.
  • Autosomes exclude sex chromosomes.
  • Different species can have very different chromosome numbers without differing in complexity.