A3.1.8—Unity and diversity of genomes within species

Members of a species share most genomic information, while alleles, SNPs, recombination, organelle DNA, and population history create individual variation.

Syllabus
First assessment 2025
Objective
A3.1.8
Level
HL

Exam analysis

Chance of appearing6%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper1
Typical marks1–2

Common command terms

  • Compare
  • Discuss
  • Determine
  • Contrast
  • State
  • Distinguish
  • Calculate

Scoring notes

Common mistake
Assuming every SNP changes the proteome rather than recognising that it always changes the genome.

Recent exam appearances

November 2025Paper1A ["HL"] · TZ322[ 1 ]A3.1.8—Unity and diversity of genomes within species
November 2024Paper3 ["HL"] · TZ012(b)[ 2 ]A3.1.8—Unity and diversity of genomes within species
May 2022Paper1 ["HL"] · TZ210[ 1 ]A3.1.8—Unity and diversity of genomes within species
May 2021Paper1 ["HL"] · TZ210[ 1 ]A3.1.8—Unity and diversity of genomes within species
May 2019Paper1 ["HL"] · TZ219[ 1 ]A3.1.8—Unity and diversity of genomes within species
Practice this objective

Coverage 2015–2025 · Updated 15 Jul 2026

Genome variation within and between species

Two DNA molecules with a single nucleotide polymorphism highlighted at one base position.

A genome is all the genetic information of an organism: protein-coding genes, non-coding DNA and, where present, non-nuclear DNA such as plasmids or organelle genomes.

Members of the same species share most genes and genome organisation but differ in variants. A single-nucleotide polymorphism (SNP) is a one-base difference that can act as a genetic marker. Variation between species is generally much greater than variation within one species, although the two distributions can overlap.

Across eukaryotes, genomes differ in total size, base sequence and chromosome organisation. A larger genome does not automatically mean a more complex organism because much DNA is non-coding and genome size can be affected by repeated sequences or polyploidy. In comparisons, state both the level (within or between species) and the feature being compared (sequence, size or organisation).

Unity and diversity of genomes within

Assessment in practice

1–2 marks
How it is assessed

This objective is assessed through essay response, commonly using Compare / Discuss / Determine.

Command terms

Compare / Discuss / Determine / Contrast / State / Distinguish / Calculate

What earns marks

Build the answer around this relationship: A genome includes all DNA in the organism, including organelle DNA where present.

Watch for

Assuming every SNP changes the proteome rather than recognising that it always changes the genome.

Representative question

Question 1

[Maximum number: 7]

Discuss the role of genes and chromosomes in determining individual and shared character features of the members of a species.

SL Transfer: Classify With Evidence

For SL, A3.1 is really one evidence map. Variation explains why individuals differ. Morphology and binomial nomenclature help group and name organisms. The biological species concept uses interbreeding and fertile offspring, but boundaries can be difficult during gradual speciation. Chromosomes and karyograms add cellular evidence. Genomes, SNPs, genome size, and whole genome sequencing add molecular evidence. The skill is choosing the right evidence for the question.

  • Variation supports natural selection.
  • Morphology groups by structure; binomial nomenclature names species universally.
  • Biological species concept uses interbreeding and fertile offspring.
  • Karyograms compare chromosome number and structure.
  • Genome evidence includes SNPs, between-species differences, genome size, and sequencing uses.

Concept essentials

  • A genome includes all DNA in the organism, including organelle DNA where present.
  • Individuals in a species share many genes but can carry different alleles.
  • Meiosis and fertilisation generate unique combinations of chromosomes and alleles.
  • SNPs are single-base genome differences that may or may not alter proteins.
  • Haplotype and allele-frequency data reveal population-level genetic diversity.