Motility is produced in the ENS through a reflex circuit involving the circular and longitudinal muscles. Nicotinic synapses between interneurons mediate the reflex circuits. When the circuit activates by the presence of a bolus, excitatory neurons in the circular muscle and inhibitory neurons in the longitudinal muscle fire producing a narrow section of bowel proximal to the bolus; this is known as the propulsive segment. Simultaneously, excitatory neurons in the longitudinal muscle and inhibitory neurons in the circular muscle fire producing the "receiving segment" of the bowel in which the bolus will continue. This process repeats with each subsequent section of the bowel.