Interpret dopamine-cell loss and motor symptoms, identify serotonin as a neurotransmitter, and trace dietary changes through gut flora and chemical production to brain effects.
Parkinson's disease occurs when dopamine-producing neurones die.
The most obvious motor symptoms of Parkinson's disease include muscle tremors and muscle rigidity.
These motor symptoms are linked to the loss of dopamine-producing neurones in the brain.
Explain why the release of reduced quantities of dopamine by presynaptic neurones could result in motor symptoms.
An answer that includes three of the following points:
- fewer dopamine molecules to bind to the \{ligand gated sodium channels/receptors\} (1)
- on the post-synaptic membrane (1)
- initiating fewer action potentials in (post-synaptic neurone) (1)
- fewer impulses sent to parts of brain controlling \{motor function / muscles\} (1)
ALLOW fewer impulses sent to muscles
/ effectors
Expert
(3)