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Edexcel A-Level Biology A2 8.20 Microarrays and Active Genes Questions

Extract mRNA from the named sample, convert or label complementary DNA, compare hybridisation signals and use the pattern to identify changed gene activity.

Syllabus
First assessment 2019
Course
Biology YBI11
Level
A2

Exam points

  • Describe extracting mRNA and detecting complementary sequences with labelled cDNA.
  • Interpret microarray signal differences to identify genes active in each sample.
  • Use bioinformatics to compare expression patterns between diseases, treatments or species.

Edexcel A-Level Biology A2 8.20 Microarrays and Active Genes Questions question 1

[Maximum number: 2]

Small variations in DNA sequences and activation of genes can explain why individuals respond differently to diseases and the drugs used to treat them.

Describe how active genes could be identified.

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