Edexcel IGCSE Biology 2.49 Ventilation role
Practise interpreting smoking and lung health data, linking oxygen use, breathlessness, lung cancer risk and circulatory disease.
- Syllabus
- First assessment 2019
- Course
- Biology 4BI1
Practise interpreting smoking and lung health data, linking oxygen use, breathlessness, lung cancer risk and circulatory disease.
The diagram shows parts of the human respiratory system with some structures labelled.

A scientist compared the rate at which oxygen is used during exercise by a person who is a non-smoker with a person who is a smoker.
The rate is measured in cm3 per minute for each kilogram of body mass.
The table shows the scientist's results.

Explain the effect of cigarette smoking on the rate at which oxygen is used.
An explanation that makes reference to three of the following:
1. oxygen use lower in smokers / lower rate of oxygen use / eq
2. tar (in cigarettes)
3. causes emphysema / mucus builds up / mucus not removed / cilia damaged / eq
4. less surface area (of alveoli) / eq
5. less diffusion of oxygen (into blood)
6. carbon monoxide binds to haemoglobin (reducing oxygen) /eq
7. causes narrowing of arteries / blocks blood vessels (reducing flow of oxygenated blood) / eq
Accept less oxygen uptake / eq Accept converse
Accept alveoli walls break down / deform / are damaged
Ignore gas exchange
Ignore veins