Edexcel IGCSE Biology co-ordination and response
Use coordination evidence from plant and animal questions: plan stimulus investigations, interpret response data and explain nerves or hormones.
- Syllabus
- First assessment 2019
- Course
- Biology 4BI1
Use coordination evidence from plant and animal questions: plan stimulus investigations, interpret response data and explain nerves or hormones.
The diagram shows a food web from a woodland ecosystem.

Woodlice feed on dead and decaying plant material in the soil. The photographs show how a woodlouse can curl up into a ball.
This behaviour is an example of a reflex response.

State what is meant by a reflex response.
- involuntary / automatic / does not involve the brain /
spontaneous / without thinking / unconscious / eq
Give a reason why this reflex response benefits the woodlouse.
• protects from predators / only exposes hard
shell /eq
danger /
harm
/injury
Read the passage below. Use the information in the passage and your own knowledge to answer the questions that follow.
Rivers - the arteries of the world
Rivers are important supplies of water for drinking, farming, industry, and leisure activities. Like our circulatory system, rivers are essential for transport, and have a homeostatic effect on nature. The biodiversity in rivers is high as they are the habitat for many different species. In many countries rivers are under threat from human impact, particularly the release of untreated sewage.
Flooding can cause untreated sewage to run into rivers from pipelines. Scientists estimated that in England and Wales during 2022, sewage was released into rivers for a total time of 300000 hours. This sewage came from 1200 different pipelines. Untreated sewage may contain fertilisers, pesticides, pathogenic bacteria, and pharmaceutical drugs.

The photograph shows sewage being released into a river. The sewage causes the growth of something called 'sewage fungus'. Sewage fungus looks like fungus but is a solid collection of several types of anaerobic bacteria. Sewage fungus is common in rivers that are polluted with untreated sewage or are near to cattle and intensive crop farms. If sewage fungus is found in a river it often indicates that the biodiversity of the river will be low.
Pesticides from agriculture are also released into rivers, and these are frequently transferred through natural food chains. Even pharmaceutical drugs, such as those containing the hormones oestrogen and progesterone, have been found in polluted rivers. These drugs must have been consumed by humans, excreted and then released into the sewage flowing into rivers.
Untreated sewage can also contain pathogenic species of bacteria that then enter rivers. If humans are infected with these bacteria, the large intestine absorbs less water, causing diarrhoea. Some of the bacteria found in sewage are resistant to antibiotics.
Scientists are looking for ways to prevent river pollution. One way is to reduce the risk of pollution from fertilisers and from cattle urine and faeces. Woodchip bioreactors are being trialled in agricultural fields that are near to rivers. These bioreactors are pits filled with woodchips and denitrifying bacteria. Water drains through these bioreactors, which helps to remove nitrates before they reach the rivers. In some countries, efforts are being made to replant forests in areas upstream of rivers to reduce river flooding and the risk of untreated sewage release.
Rivers have a homeostatic effect on nature. This is similar to the role of homeostasis in humans.
State what is meant by the term homeostasis (lines 2 and 3).
An answer that makes reference to one of the following points:
- maintenance of constant (internal) conditions in body / eq
- control / regulating / maintaining internal conditions / eq
- control / regulating / maintaining internal environment / eq
- keeping conditions in body the same / within a (narrow) range / eq
Ignore just examples e.g. temperature /
water
Oestrogen and progesterone in polluted water lower the levels of FSH and LH in mammals.
State why lower levels of FSH can reduce fertility in mammals.
An answer that makes reference to one of the following points:
- eggs / ova / follicles, do not mature / do not grow / eq
- (FSH is required to) mature eggs / ova / follicles
- (low FSH leads to) less oestrogen / (FSH) stimulates oestrogen release
Accept female gametes
Ignore prevents ovulation / FSH stimulates ovulation
State why lower levels of LH can reduce fertility in mammals.
An answer that makes reference to one of the following points:
- no ovulation occurs / egg not released / ova not released / eq
- LH / it stimulates ovulation / LH / it stimulates egg release / eq
- (lower LH leads to) less progesterone / LH / it stimulates progesterone
Accept female
gametes
The diagram shows a human reflex arc with some structures labelled. It is the withdrawal reflex, which allows a person to remove their hand from a hot object quickly.

Which structure is the sensory receptor?
L
P
Q
S
A
Which structure is the cell body of the relay neurone?
L
N
M
P
D
Which structure is the motor neurone?
L
M
R
S
C
Which structure is the effector?
L
M
Q
S
D
A nerve impulse travels at 50 metres per second.
The length of the nerve pathway in the withdrawal reflex arc is 180 cm .
The time a person takes to remove their hand away from a hot object is called the response time.
Explain why the actual response time is different from the time taken for a nerve impulse to travel 180 cm .
An explanation that makes reference to four of the following
1. response time slower / longer /delay / (more) time taken / eq
2. (delay / transmission ) between neurones / in between neurones / not just speed along neurones / eq
3. (includes time) to generate impulse (in receptor) / (time) for muscle to contract / eq
4. chemical coordination / diffusion / eq
5. synapse
6. neurotransmitter / named neurotransmitter
ignore impulse travels faster
synapses between neurones scores mp 2 and 5